HIGH-RESOLUTION COMPUTED-TOMOGRAPHY OF THE NORMAL RAT NEPHROGRAM
HIGH-RESOLUTION COMPUTED-TOMOGRAPHY OF THE NORMAL RAT NEPHROGRAM
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DOI：
10.1097/00004424-198003000-00010
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发表时间：
1980-01-01
影响因子：
6.7
通讯作者：
BARRETT, HH
中科院分区：
文献类型：
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作者：
KUJOORY, MA;HILLMAN, BJ;BARRETT, HH
本研究描述了一种独特的，电影记录的计算机断层扫描（CT）系统和它的使用在研究对比剂之间的流动解剖室的大鼠肾脏。CT装置，由一个微焦点管，旋转动物载体，电影盒翻译，和控制电子设备，被用来暴露“正弦图”的3：1放大率通过正常大鼠的肾脏之前和2，15，30，60，和120分钟后静脉注射造影剂。显微密度测定和计算机重建得到的CT图像代表1 mm厚的冠状面，横向分辨率为150 [micro] m。利用这种新的超高分辨率CT技术，在我们的小动物模型中描述了皮质和髓质肾造影成分的吸收系数的时间变化，用于对比流研究。
This study describes a unique, film-recorded computed tomography (CT) system and its use in studying contrast flow between anatomic compartments of the rat kidney. The CT apparatus, composed of a microfocal spot tube, rotating animal carrier, film-cassette translator, and control electronics, was used to expose" sinograms" of 3: 1 magnification through the kidneys of normal rats prior to and 2, 15, 30, 60, and 120 minutes after intravenous contrast injection. Microdensitometry and computer reconstruction resulted in CT images representing 1-mm thick coronal sections with lateral resolution of 150 [micro] m. With this novel technique of ultrahigh-resolution CT, temporal alterations in absorption coefficient of cortical and medullary nephrographic components were depicted for contrast flow study in our small animal model.