Amberlite IRA900N3 as a new catalyst for the azidation of α,β-unsaturated ketones under solvent-free conditions
Amberlite IRA900N3 as a new catalyst for the azidation of α,β-unsaturated ketones under solvent-free conditions
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DOI：
10.1021/jo061791b
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发表时间：
2006-12-08
影响因子：
3.6
通讯作者：
Vaccaro, Luigi
中科院分区：
文献类型：
--
作者：
Castrica, Luca;Fringuelli, Francesco;Vaccaro, Luigi
Amberlite IRA 900 N（3）是一种优良的有机催化剂，可在无溶剂条件下用于α，β-不饱和酮与叠氮三甲基硅的叠氮化反应。通过避免使用金属物质和有机反应介质，该方法是在温和条件下制备β-叠氮基酮的绿色工具，产率从良好到优异。催化剂可以回收和重复使用，而不会损失其效率。
Amberlite IRA900N(3) is an excellent organocatalyst for the azidation of alpha,beta-unsaturated ketones with trimethylsilyl azide under solvent-free conditions. By avoiding the use of metallic species and of the organic reaction medium, the procedure is a green tool for the preparation of beta-azido ketones under mild conditions with yields from good to excellent. The catalyst can be recovered and re-used with no loss of its efficiency.