Binge-eating disorder and the outcome of bariatric surgery in a prospective, observational study: Two-year results.
Binge-eating disorder and the outcome of bariatric surgery in a prospective, observational study: Two-year results.
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DOI：
10.1002/oby.21648
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发表时间：
2016-11
期刊：
影响因子：
--
通讯作者：
Williams NN
中科院分区：
文献类型：
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作者：
Chao AM;Wadden TA;Faulconbridge LF;Sarwer DB;Webb VL;Shaw JA;Thomas JG;Hopkins CM;Bakizada ZM;Alamuddin N;Williams NN
我们以前报道过，术前暴饮暴食症（BED）并没有减轻减肥手术后12个月的体重减轻。本报告通过检查24个月时的体重减轻来扩展我们先前的研究。我们使用改良的意向治疗（ITT）人群，比较了59名接受减肥手术治疗的参与者（术前确定无当前饮食失调）24个月的体重变化，以及33名接受减肥手术治疗的BED参与者的体重变化。研究人员还将这些变化与49名肥胖和卧床不起的人进行了比较，这些人寻求改变生活方式以减轻体重。分析包括所有可用的数据点，并针对协变量进行了调整。在第24个月，术前接受过外科治疗的BED患者的初始体重下降了18.6%，而没有BED的患者为23.9%（p=0.049）。(Mean第12个月时的损失分别为21.5%和24.2%; p=0.23。接受生活方式改变的BED参与者在24个月时下降了5.6%，显著低于两组手术治疗的患者（p<0.001）。这些结果表明，术前床衰减减肥手术后的长期体重减轻。我们建议患有这种疾病的患者，以及其他饮食失调，接受持续的行为支持，其时间仍有待确定。
We previously reported that preoperative binge eating disorder (BED) did not attenuate weight loss 12 months after bariatric surgery. This report extends our prior study by examining weight loss at 24 months. We used a modified intention-to-treat (ITT) population to compare 24-month changes in weight among 59 participants treated with bariatric surgery, determined preoperatively to be free of a current eating disorder, with changes in 33 surgically-treated participants with BED. Changes were also compared with 49 individuals with obesity and BED who sought lifestyle modification for weight loss. Analyses included all available data points and were adjusted for covariates. At month 24, surgically-treated patients with BED preoperatively lost 18.6% of initial weight, compared with 23.9% for those without BED (p=0.049). (Mean losses at month 12 had been 21.5% and 24.2%, respectively; p=0.23.) Participants with BED who received lifestyle modification lost 5.6% at 24 months, significantly less than both groups of surgically treated patients (p<0.001). These results suggest that preoperative BED attenuates long-term weight loss after bariatric surgery. We recommend that patients with this condition, as well as other eating disturbances, receive adjunctive behavioral support, the timing of which remains to be determined.