Performance on tests sensitive to impaired executive ability in schizophrenia, mania and well controls: acute and subacute phases
Performance on tests sensitive to impaired executive ability in schizophrenia, mania and well controls: acute and subacute phases
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DOI：
10.1016/s0920-9964(97)00070-4
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发表时间：
1997-08-29
影响因子：
4.5
通讯作者：
Clair, A
中科院分区：
文献类型：
--
作者：
McGrath, J;Scheldt, S;Clair, A
目的：比较精神分裂症、躁狂症和良好对照组在对执行能力受损的敏感测试中的表现，并评估这些措施在精神病急性期和亚急性期的稳定性。方法：对36例新入院的精神分裂症患者、18例躁狂症患者和20例正常对照组进行为期4周的两次评定。测试包括：受控口语单词联想测试、Stroop测试、威斯康星卡片分类测试和连线测试。结果：与对照组相比，两组患者在两个时间点的Stroop测试均显著受损。在时间1的连线测验和时间2的威斯康星卡片分类测验上也发现了显著的组间差异。当控制练习效果时，精神分裂症组的Stroop和连线测验以及躁狂组的WCST类别随着时间的推移有显著的改善。讨论：与对照组相比，患者组在与执行能力相关的指标上受到损害。精神分裂症患者和躁狂症患者在急性期和亚急性期之间考试成绩的改善模式不同。(C)1997年爱思唯尔科学公司。
Aims: To compare the performance of schizophrenia, mania and well control groups on tests sensitive to impaired executive ability, and to assess the within-group stability of these measures across the acute and subacute phases of psychoses. Method: Recently admitted patients with schizophrenia (n=36), mania (n=18) and a well control group (n=20) were assessed on two occasions separated by 4 weeks. Tests included: the Controlled Oral Word Association Test, the Stroop Test, the Wisconsin Card Sort Test, and the Trail Making Test. Results: The two patient groups were significantly impaired on the Stroop Test at both time points compared to the control group. Significant group differences were also found for the Trail Making Test at Time 1 and for the Wisconsin Card Sort Test at Time 2. When controlled for practice effect, significant improvements over time were found on the Stroop and Trail Making tests in the schizophrenia group and on WCST Categories Achieved in the mania group. Discussion: Compared to controls, the patient groups were impaired on measures related to executive ability. The pattern of improvement on test scores between the acute and subacute phases differed between patients with schizophrenia versus patients with mania. (C) 1997 Elsevier Science B.V.