Research fundamentals: Selection and development of clinical outcome measures
Research fundamentals: Selection and development of clinical outcome measures
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DOI：
10.1111/j.1553-2712.2000.tb02249.x
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发表时间：
2000-04-01
影响因子：
4.4
通讯作者：
Hollander, JE
中科院分区：
文献类型：
--
作者：
Singer, AJ;Thode, HC;Hollander, JE
临床结果衡量患者的健康或幸福感。临床试验或研究中使用的结果衡量标准的选择是复杂的。如果不存在适当的结果衡量标准，这就更加困难，需要制定一种新的衡量标准。理想的临床结果应该是可信的、全面的、对变化敏感、准确、生物学上敏感和可行的。本文描述了临床结果的属性，并以作者开发伤口美容结果测量的经验为例，说明了如何开发新的结果。
Clinical outcomes measure patient health or well-being. The choice of an outcome measure for use in a clinical trial or study is complex. It is even more difficult when no appropriate outcome measure exists, necessitating the development of a novel one. The ideal clinical outcome should be credible, comprehensive, sensitive to change, accurate, biologically sensible, and feasible. This paper describes the attributes of clinical outcomes and illustrates how to develop novel outcomes, using as an example the authors' experience in developing a wound cosmesis outcome measure.