Change the preprocedural fasting policy for contrast-enhanced CT: results of 127,200 cases.
Change the preprocedural fasting policy for contrast-enhanced CT: results of 127,200 cases.
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改变增强 CT 术前禁食政策：127,200 例病例的结果
DOI：
10.1186/s13244-022-01173-z
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发表时间：
2022-02-24
影响因子：
4.7
通讯作者：
Li X
中科院分区：
文献类型：
--
作者：
Liu H;Zhao L;Liu J;Lan F;Cai L;Fang J;Li X
ObjectivesTo analyze the relationship between the dietary preparation status prior to contrast-enhanced CT (CECT) and adverse drug reactions (ADR) and emetic complications.MethodsNon-emergency adult patients who underwent routine CECT in our hospital from January 2019 to December 2020 were retrospectively analyzed. Stratified dietary preparation regimens were implemented for different clinical scenarios. The relationship between actual dietary preparation status and ADR and emetic complications was analyzed.ResultsA total of 127,200 cases were enrolled, including 49,676 cases in the fasting group (57 years ± 13, 56.79% men) and 77,524 cases in the non-fasting group (60 years ± 13, 54.55% men). No statistical difference was found in the overall incidence of ADR (0.211% vs. 0.254%,p= 0.126) or emetic complications (0.030% vs. 0.046%,p= 0.158) between the two groups, and no aspiration pneumonia or death occurred. For patients with an ICM-ADR history, the ADR incidence in non-fasting group was significantly lower than fasting group (2.424% vs. 12.371%,p= 0.002). For patients with hypertension, injection dose ≥ 100 mL, injection rate ≥ 5 mL/s, and Iopromide 370 usage, non-fasting was associated with higher ADR incidence (p< 0.05). 36.67% of the patients experienced unnecessary excessive fasting in practice. Excessive fasting (≥ 10 h) and more water ingestion (≥ 500 mL) within 1 h prior to CECT were associated with higher ADR incidence (p< 0.05).ConclusionUnrestricted food ingestion would not increase the overall risk of ADR and emetic complications. For some special patient subgroups, non-fasting, excessive fasting, and more water ingestion were associated with higher ADR incidence.
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