Investigation of Crystal Surface Finish and Geometry on Single LYSO Scintillator Detector Performance for Depth-of-Interaction Measurement with Silicon Photomultipliers.
Investigation of Crystal Surface Finish and Geometry on Single LYSO Scintillator Detector Performance for Depth-of-Interaction Measurement with Silicon Photomultipliers.
复制标题
对单个Lyso闪烁体检测器性能的晶体表面饰面和几何形状的研究，以用硅光电倍增体进行深度相互作用测量。
DOI：
10.1016/j.nima.2012.07.029
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发表时间：
2012-11-21
期刊：
影响因子：
--
通讯作者：
Shao Y
中科院分区：
文献类型：
--
作者：
Bircher C;Shao Y
交互深度（DOI）信息可以提高从正电子发射断层扫描（PET）获取的重建图像的质量，特别是在专用于乳腺、脑或小动物成像应用的高分辨率和紧凑型扫描仪中。此外，具有飞行时间能力的临床扫描仪也可以从DOI信息中受益。确定晶体中DOI的最有前途的方法之一涉及阅读来自闪烁晶体两端的信号，并计算两个检测器之间的信号比。已知该方法与高度抛光的晶体相比，在粗糙晶体的情况下提供更好的DOI分辨率。然而，仍然没有很好地研究的是，作为晶体表面处理和几何形状的函数，使用硅光电倍增管（SiPM）作为光电探测器，在空间、能量、时间和DOI分辨率之间涉及多少权衡。本研究探讨不同的晶体表面光洁度和几何形状的能量，时间和DOI分辨率在不同的晶体深度的影响。结果表明，对于1.5×1.5×20 mm ~ 3和2×2×20 mm ~ 3的LYSO晶体，在0.5 ~ 30 μ m的表面粗糙度范围内，其能量分辨率和符合时间分辨率几乎保持不变，在不同晶深上分别为15%和2.4 ns，而DOI分辨率从差于5 mm稳定地提高到好于2 mm。他们证明，通过适当的表面处理，对所检查的晶体中的能量和符合定时分辨率没有显著影响，并且似乎在提高DOI分辨率和降低其他检测器性能之间没有折衷。这些结果将是有价值的，以指导选择晶体表面条件的开发DOI可测量的PET探测器与耦合到SiPM阵列的全阵列的LYSO振荡器。
Depth of Interaction (DOI) information can improve quality of reconstructed images acquired from Positron Emission Tomography (PET), especially in high resolution and compact scanners dedicated for breast, brain, or small animal imaging applications. Additionally, clinical scanners with time of flight capability can also benefit from DOI information. One of the most promising methods of determining DOI in a crystal involves reading the signal from two ends of a scintillation crystal, and calculating the signal ratio between the two detectors. This method is known to deliver a better DOI resolution with rough crystals compared to highly polished crystals. However, what is still not well studied is how much of a tradeoff is involved between spatial, energy, temporal, and DOI resolutions as a function of the crystal surface treatment and geometry with the use of Silicon Photomultipliers (SiPM) as the photo detectors. This study investigates the effects of different crystal surface finishes and geometries on energy, timing and DOI resolutions at different crystal depths. The results show that for LYSO scintillators of 1.5×1.5×20 mm3 and 2×2×20 mm3 with their surfaces finished from 0.5 to 30 micron roughness, almost the same energy and coincidence timing resolutions were maintained, around 15% and 2.4 ns respectively across different crystal depths, while the DOI resolutions were steadily improved from worse than 5 mm to better than 2 mm. They demonstrate that crystal roughness, with proper surface preparing, does not have a significant effect on the energy and coincidence timing resolutions in the crystals examined, and there does not appear to be a tradeoff between improving DOI resolution and degrading other detector performances. These results will be valuable to guide the selection of crystal surface conditions for developing a DOI measurable PET detector with a full array of LYSO scintillators coupled to SiPM arrays.
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