Gold nanoparticle based dot-blot immunoassay for sensitively detecting Alzheimer's disease related β-amyloid peptide.
Gold nanoparticle based dot-blot immunoassay for sensitively detecting Alzheimer's disease related β-amyloid peptide.
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DOI：
10.1039/c2cc33568a
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发表时间：
2012-07
影响因子：
4.9
通讯作者：
Chengke Wang;Dianjun Liu;Zhenxin Wang
中科院分区：
文献类型：
--
作者：
Chengke Wang;Dianjun Liu;Zhenxin Wang
A simple, sensitive gold nanoparticle (GNP)-based dot-blot immunoassay has been developed for detecting Alzheimer's disease related β-amyloid peptide 1-42 (Aβ(1-42)) down to a 50 pg mL(-1) level in aqueous solution. Practical samples (cerebrospinal fluid (CSF), cell culturing mediums and cell lysates) have been used to demonstrate the ability of the assay.
