Early and definitive diagnosis of toxic shock syndrome by detection of marked expansion of T-cell-receptor Vβ2-positive T cells

Early and definitive diagnosis of toxic shock syndrome by detection of marked expansion of T-cell-receptor Vβ2-positive T cells
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DOI:
10.3201/eid0903.020360
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发表时间:
2003-03-01
影响因子:
11.8
通讯作者:
Uchiyama, T
Uchiyama, T
中科院分区:
医学2区
文献类型:
--
作者:
Matsuda, Y;Kato, H;Uchiyama, T

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我们描述了两例早期中毒性休克综合征,由耐甲氧西林金黄色葡萄球菌产生的超抗原引起,并根据T细胞受体vbeta2阳性T细胞的扩增进行诊断。1例患者出现非典型症状。我们的结果表明,诊断系统结合实验室技术是必不可少的快速,明确诊断中毒性休克综合征。
We describe two cases of early toxic shock syndrome, caused by the superantigen produced from methicillin-resistant Staphylococcus aureus and diagnosed on the basis of an expansion of T-cell-receptor Vbeta2-positive T cells. One case-patient showed atypical symptoms. Our results indicate that diagnostic systems incorporating laboratory techniques are essential for rapid, definitive diagnosis of toxic shock syndrome.