Interactions between Stimulus-Specific Adaptation and Visual Auditory Integration in the Forebrain of the Barn Owl
Interactions between Stimulus-Specific Adaptation and Visual Auditory Integration in the Forebrain of the Barn Owl
复制标题
DOI：
10.1523/jneurosci.5723-09.2010
复制
发表时间：
2010-05-19
影响因子：
5.3
通讯作者：
Gutfreund, Yoram
中科院分区：
文献类型：
--
作者：
Reches, Amit;Netser, Shai;Gutfreund, Yoram
神经适应和视听整合是大脑中两种常见的现象，但对它们之间的相互作用却知之甚少。在本研究中，我们调查了仓鸮的视觉前脑区，内皮层（E），最近已被证明包括听觉反应以及。神经元对视觉、听觉和双峰（视觉和听觉一起）事件序列的反应进行了分析。序列包括两个刺激，一个具有低发生概率，另一个具有高发生概率。E区神经元对低概率视觉刺激的反应比对高概率视觉刺激的反应更强烈。这种现象被称为刺激特异性适应（SSA），被认为是变化检测的神经相关。相应的听觉序列的反应没有显示出相同的趋势。有趣的是，然而，SSA双峰事件是强于视觉事件单独。这种增强是明显的视觉和听觉刺激时，从匹配的位置在空间（一致），但不是当双峰刺激空间不一致。这些研究结果表明，正在进行的任务检测意外事件可以受益于视觉和听觉信息的整合。
Neural adaptation and visual auditory integration are two well studied and common phenomena in the brain, yet little is known about the interaction between them. In the present study, we investigated a visual forebrain area in barn owls, the entopallium (E), which has been shown recently to encompass auditory responses as well. Responses of neurons to sequences of visual, auditory, and bimodal (visual and auditory together) events were analyzed. Sequences comprised two stimuli, one with a low probability of occurrence and the other with a high probability. Neurons in the E tended to respond more strongly to low probability visual stimuli than to high probability stimuli. Such a phenomenon is known as stimulus-specific adaptation (SSA) and is considered to be a neural correlate of change detection. Responses to the corresponding auditory sequences did not reveal an equivalent tendency. Interestingly, however, SSA to bimodal events was stronger than to visual events alone. This enhancement was apparent when the visual and auditory stimuli were presented from matching locations in space (congruent) but not when the bimodal stimuli were spatially incongruent. These findings suggest that the ongoing task of detecting unexpected events can benefit from the integration of visual and auditory information.