General and specific components of depression and anxiety in an adolescent population.
General and specific components of depression and anxiety in an adolescent population.
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DOI：
10.1186/1471-244x-11-191
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发表时间：
2011-12-07
期刊：
影响因子：
4.4
通讯作者：
Croudace TJ
中科院分区：
文献类型：
--
作者：
Brodbeck J;Abbott RA;Goodyer IM;Croudace TJ
抑郁和焦虑症状经常同时发生，导致关于抑郁和焦虑的共同和独特特征的争论。探索性因素分析（EFA）和双因素建模方法被用来分离一般困扰连续更具体的子领域的抑郁和焦虑的青少年社区样本（n = 1159，年龄14）。研究工具为情绪与情感问卷及儿童显性焦虑量表。一个三因素的验证性因素分析的报告，确定a）情绪和社会认知症状的抑郁症，B）令人担忧的症状，和c）躯体和信息处理症状作为不同但密切相关的结构。随后的双因素建模支持一般的困扰因素，占的共同性的抑郁和焦虑的项目。绝望自杀的想法和不安疲劳的具体因素表明不同的精神病理结构，占独特的信息和以上的一般困扰因素。女性的一般困扰因子和绝望自杀因子较男性重，而不安疲劳因子则较男性重。一般遇险因素的测量精度更高，跨越更广泛的人口比任何三个一阶因素。一般的痛苦因素提供了最可靠的流行病学分析的目标，但具体的因素可能有助于完善有效的表型维度的病因学研究，并协助未来的精神病发作的预后建模。
Depressive and anxiety symptoms often co-occur resulting in a debate about common and distinct features of depression and anxiety. An exploratory factor analysis (EFA) and a bifactor modelling approach were used to separate a general distress continuum from more specific sub-domains of depression and anxiety in an adolescent community sample (n = 1159, age 14). The Mood and Feelings Questionnaire and the Revised Children's Manifest Anxiety Scale were used. A three-factor confirmatory factor analysis is reported which identified a) mood and social-cognitive symptoms of depression, b) worrying symptoms, and c) somatic and information-processing symptoms as distinct yet closely related constructs. Subsequent bifactor modelling supported a general distress factor which accounted for the communality of the depression and anxiety items. Specific factors for hopelessness-suicidal thoughts and restlessness-fatigue indicated distinct psychopathological constructs which account for unique information over and above the general distress factor. The general distress factor and the hopelessness-suicidal factor were more severe in females but the restlessness-fatigue factor worse in males. Measurement precision of the general distress factor was higher and spanned a wider range of the population than any of the three first-order factors. The general distress factor provides the most reliable target for epidemiological analysis but specific factors may help to refine valid phenotype dimensions for aetiological research and assist in prognostic modelling of future psychiatric episodes.