CONE BIPOLAR CELLS AND CONE SYNAPSES IN THE PRIMATE RETINA
CONE BIPOLAR CELLS AND CONE SYNAPSES IN THE PRIMATE RETINA
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DOI：
10.1017/s0952523800010932
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发表时间：
1991-07-01
影响因子：
1.9
通讯作者：
HOPKINS, JM
中科院分区：
文献类型：
--
作者：
BOYCOTT, BB;HOPKINS, JM
灵长类视网膜双极细胞与两个相邻的视锥(2C双极)突触的进一步描述。它们的突触接触要么作为锥体三联体的中心(内陷)成分，要么作为锥体椎弓根基底膜上的基底部(扁平)接触。相应地，它们的轴突终止于内网状层的b(内)半部分或a(外)半部分。2C双极轴突终末的形状和大小与相邻的侏儒双极无法区分。因此，2C双极像侏儒双极一样，很可能与侏儒神经节细胞突触。两个C双极尚未被确定为与中心凹锥体有关。但它们并不像以前认为的那样局限于视网膜外围，因为它们发生时，与侏儒(单锥)双极细胞混合在一起，从距中心凹约2.5毫米到至少10.0毫米的视网膜所有部分。2C双极很可能是侏儒双极的变种；它们联系的是同一种群的锥体中的一些成员，而不是侏儒。本文对目前对侏儒、2C和弥漫锥体双极细胞突触连接模式的认识进行了简要的回顾，并提出了一些新的问题。
Primate retinal bipolar cells synapsing with two adjacent cones (2C bipolars) are further described. Their synaptic contacts are either as the central (invaginating) component of the cone triads or as basal (flat) contacts on the membrane of the cone pedicle base. Correspondingly, their axons end either in the b (inner) half or in the a (outer) half of the inner plexiform layer. The shape and size of the axon terminals of 2C bipolars are indistinguishable from those of adjacent midget bipolars. Therefore 2C bipolars, like midget bipolars, probably synapse with midget ganglion cells. Two C bipolars have not been identified as connected to foveal cones. But they are not restricted to the retinal periphery, as has previously been supposed, since they occur, mixed with midget (single cone) bipolars, throughout all parts of the retina from about 2.5 mm to at least 10.0 mm from the fovea. It is likely that 2C bipolars are a variant of the midget bipolars; and that they contact some members of the same population of cones, instead of the midgets. This paper briefly reviews, and raises some new, problems concerning our current understanding of the synaptic connectivity patterns of the midget, 2C, and diffuse cone bipolar cells.