Liver function assessment using 99mTc-GSA single-photon emission computed tomography (SPELT)/CT fusion imaging in hilar bile duct cancer: A retrospective study
Liver function assessment using 99mTc-GSA single-photon emission computed tomography (SPELT)/CT fusion imaging in hilar bile duct cancer: A retrospective study
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DOI：
10.1016/j.surg.2016.02.009
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发表时间：
2016-07-01
期刊：
影响因子：
3.8
通讯作者：
Morita, Sojiro
中科院分区：
文献类型：
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作者：
Sumiyoshi, Tatsuaki;Shima, Yasuo;Morita, Sojiro
背景。本研究的目的是确定tc -99m-二乙烯三胺-五乙酸-半乳糖人血清白蛋白（Tc-99m-GSA）单品的效用。光子发射计算机断层扫描(SPECT)/CT融合成像评估肝门部胆管癌患者术后残余肝功能。回顾性分析30例肝门部胆管癌行肝大切除术合并肝外胆管切除术的患者。采用吲吲胺绿血浆清除率（KICG）值和估计的KICG (99m) tc - gsa闪烁成像（KGSA）和Tc-99m-GSA SPECT/CT融合成像的未来残肝体积和功能率分别评估术前全肝功能和术后残肝功能。剩余（rem） KICG （= KICG X体积率）和remKGSA （= KGSA X功能率）用于预测未来剩余肝功能；大肝切除术被认为是不安全的价值
Background. The objective of this study was to determine the utility of Tc-99m-diethylenetriamine-penta-acetic acid-galactosyl human serum albumin (Tc-99m-GSA) single. photon emission computed tomography (SPECT)/CT fusion imaging for posthepatectomy remnant liver function assessment in hilar bile duct cancer patients.Methods. Thirty hilar bile duct cancer patients who underwent major hepatectomy with extrahepatic bile duct resection were retrospectively analyzed. Indocyanine green plasma clearance rate (KICG) value and estimated KICG (99m)iTc-GSA scintigraphy (KGSA) and volumetric and functional rates of future remnant liver by Tc-99m-GSA SPECT/CT fusion imaging were used to evaluate preoperative whole liver function and posthepatectomy remnant liver function, respectively. Remnant (rem) KICG (= KICG X volumetric rate) and remKGSA (= KGSA X functional rate) were used to predict future remnant liver function; major hepatectomy was considered unsafe for values