The Botany Array Resource: e-Northerns, Expression Angling, and Promoter analyses

The Botany Array Resource: e-Northerns, Expression Angling, and Promoter analyses
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DOI:
10.1111/j.1365-313x.2005.02437.x
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发表时间:
2005-07-01
期刊:
影响因子:
7.2
通讯作者:
Provart, NJ
Provart, NJ
中科院分区:
生物学1区
文献类型:
--
作者:
Toufighi, K;Brady, SM;Provart, NJ

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植物阵列资源提供了获取和存档拟南芥微阵列数据的方法,以及生物学家友好的工具,用于查看和挖掘我们自己和其他人的数据,例如来自 AtGenExpress 联盟的数据。产生的所有数据均可通过数据库的网络界面公开获取:http://bbc.botany.utoronto.ca。该数据库是根据微阵列实验的最低信息设计的 [Brazma, A., Hingamp, P., Quackenbush, J. 等人。 (2001) 有关微阵列实验 (MIAME) 的最低信息 - 面向微阵列数据标准。纳特。 Genet.29, 365]约定-所有表达数据都与相应的实验细节相关联。该数据库是可搜索的,它还为研究人员提供了一组有用且易于使用的基于网络的数据挖掘工具,并提供复杂但易于理解的输出图形。其中包括用于执行“电子北方”的表达浏览器、用于识别与感兴趣的基因共同调节的基因的表达钓鱼器、以及用于识别单个或共同调节基因的启动子中潜在顺式元件的启动子。
The Botany Array Resource provides the means for obtaining and archiving microarray data for Arabidopsis thaliana as well as biologist-friendly tools for viewing and mining both our own and other's data, for example, from the AtGenExpress Consortium. All the data produced are publicly available through the web interface of the database at http://bbc.botany.utoronto.ca. The database has been designed in accordance with the Minimum Information About a Microarray Experiment [Brazma, A., Hingamp, P., Quackenbush, J. et al. (2001) Minimum information about a microarray experiment (MIAME) - toward standards for microarray data. Nat. Genet.29, 365] convention - all expression data are associated with the corresponding experimental details. The database is searchable and it also provides a set of useful and easy-to-use web-based data-mining tools for researchers with sophisticated yet understandable output graphics. These include Expression Browser for performing 'electronic Northerns', Expression Angler for identifying genes that are co-regulated with a gene of interest, and Promomer for identifying potential cis-elements in the promoters of individual or co-regulated genes.