Occupational exposure to electromagnetic fields and breast cancer in men.
Occupational exposure to electromagnetic fields and breast cancer in men.
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DOI：
10.1093/oxfordjournals.aje.a116095
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发表时间：
1991-08
影响因子：
5
通讯作者：
P. Demers;D. Thomas;D. Thomas;K. Rosenblatt;K. Rosenblatt;L. Jimenez;L. Jimenez;A. McTiernan;H. Stalsberg;A. Stemhagen;W. Thompson;M. G. Curnen;W. Satariano;D. Austin;P. Isacson;R. Greenberg;C. Key;L. Kolonel;D. West
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文献类型：
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作者：
P. Demers;D. Thomas;D. Thomas;K. Rosenblatt;K. Rosenblatt;L. Jimenez;L. Jimenez;A. McTiernan;H. Stalsberg;A. Stemhagen;W. Thompson;M. G. Curnen;W. Satariano;D. Austin;P. Isacson;R. Greenberg;C. Key;L. Kolonel;D. West
一项以人群为基础的男性乳腺癌病例对照研究的数据被用来检验职业暴露于电磁场会增加乳腺癌风险的假设。1983-1987年间诊断的病例(n=227)来自国家癌症研究所监测、流行病学和最终结果项目的10个基于人群的癌症登记。对照组(n=300)通过随机数字拨号和从医疗保险资格列表中选择。暴露状态被定义为曾经受雇于被归类为可能暴露于电磁场的工作，在不知道病例/控制状态的情况下分配。有接触史的职业风险较高(OR=1.8，95%可信区间(CI)1.0~3.7)，其中电工、电话线工、电力工人(OR=6.0，95%CI 1.7~21)和无线电通信工人(OR=2.9，95%CI 0.8~10)风险最高。风险不随接触工龄而变化。风险最高的是那些在30岁之前首次受雇于接触过的工作的受试者，以及在确诊前至少30年首次接触过的受试者。这些结果支持了电磁场可能与男性乳腺癌有关的理论。这一假设值得在女性身上进行评估。
Data from a population-based case-control study of breast cancer in men were used to examine the hypothesis that occupational exposure to electromagnetic fields increases the risk of breast cancer. Incident cases (n = 227) diagnosed between 1983 and 1987 were obtained from 10 population-based cancer registries of the Surveillance, Epidemiology, and End Results program of the National Cancer Institute. Controls (n = 300) were selected by random digit dialing and from Medicare eligibility lists. Exposure status, defined as ever having been employed in a job which has been classified as involving potential exposure to electromagnetic fields, was assigned without knowledge of case/control status. An elevated risk was found for any job with exposure (odds ratio (OR) = 1.8, 95 percent confidence interval (CI) 1.0-3.7), and risk was highest among electricians, telephone linemen, and electric power workers (OR = 6.0, 95 percent CI 1.7-21) and radio and communications workers (OR = 2.9, 95 percent CI 0.8-10). Risk did not vary with duration of exposed employment. The risk was highest among subjects who were first employed in jobs with exposure before the age of 30 years and who were initially exposed at least 30 years prior to diagnosis. These results lend support to the theory that electromagnetic fields may be related to breast cancer in men. The hypothesis warrants evaluation in women.