Noninvasive measures of bone bending rigidity in the monkey (M. nemestrina)
Noninvasive measures of bone bending rigidity in the monkey (M. nemestrina)
复制标题
猴子骨弯曲刚度的无创测量（M. nemestrina）
DOI：
10.1007/bf02441171
复制
发表时间：
1979
影响因子：
4.2
通讯作者：
C. Steele
中科院分区：
文献类型：
--
作者：
D. Young;W. H. Howard;C. Cann;C. Steele
测定猕猴尺骨和胫骨的体内抗弯硬度和骨矿含量。用阻抗探针法测量椎体前后平面的弯曲刚度。用机电振荡器诱导骨骼的强迫振动，并测定驱动力和速度。利用100-250赫兹范围内的响应来计算弯曲刚度。用光子吸收技术测定横切面中的骨矿含量。对17只体重6-14公斤的雄性恒河猴(Macaca Nomestrina)进行了评价。刚性测量的重复性为4%。骨矿含量的测量精度为3.5%。抗弯硬度与横截面矿物质含量呈正相关，r=0.899。两只猴子在长时间的低动力束缚下接受了评估。束缚造成局部骨丢失，尤以胫骨近端最为明显。局部骨矿含量下降17%至24%，平均抗弯硬度下降12%至22%。讨论了骨骼的变化导致矿物质含量和硬度的减少。
SummaryThe in vivo bending rigidity and bone mineral content of monkey ulnae and tibiae were measured. Bending rigidity in the anteroposterior plane was measured by an impedance probe technique. Forced vibrations of the bones were induced with an electromechanical shaker, and force and velocity at the driving point were determined. The responses over the range of 100–250 Hz were utilized to compute the bending rigidity. Bone mineral content in the cross section was determined by a photon absorption technique. Seventeen male monkeys (Macaca nemestrina) weighing 6–14 kg were evaluated. Repeatability of the rigidity measures was 4%. Bone mineral content was measured with a precision of 3.5%. Bending rigidity was correlated with the mineral content of the cross section,r=0.899. Two monkeys were evaluated during prolonged hypodynamic restraint. Restraint produced regional losses of bone most obviously in the proximal tibia. Local bone mineral content declines 17 to 24% and the average bending rigidity declines 12 to 22%. Changes in bones leading to a reduction in mineral content and stiffness are discussed.