Correlates of quality of life in older adults with diabetes: the diabetes & aging study.
Correlates of quality of life in older adults with diabetes: the diabetes & aging study.
复制标题
糖尿病老年人的生活质量相关：糖尿病和衰老研究。
DOI：
10.2337/dc10-2424
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发表时间：
2011-08
期刊：
影响因子：
16.2
通讯作者：
Huang ES
中科院分区：
文献类型：
--
作者：
Laiteerapong N;Karter AJ;Liu JY;Moffet HH;Sudore R;Schillinger D;John PM;Huang ES
评估老年糖尿病患者的健康相关生活质量 (HRQL) 与老年综合征、糖尿病并发症和低血糖之间的关联。对 6,317 名年龄在 60 至 75 岁的 2 型或 1 型糖尿病成人进行种族分层随机抽样，他们在北加州 Kaiser Permanente 完成了一项调查，其中包括基于简式 8 项健康调查的 HRQL 工具。管理记录用于确定老年综合征、糖尿病并发症和低血糖的诊断。在特定暴露模型和组合暴露模型（任何综合征、任何并发症或低血糖）中估计 HRQL 与暴露之间的关联。保守地说，≥3分的差异被认为是HRQL评分的最小重要差异。几乎所有感兴趣的风险暴露的 HRQL 都较低。最低的身体 HRQL 与截肢相关。在组合暴露模型中，老年综合征（-5.3 [95% CI -5.8 至 -4.8]，P < 0.001）和糖尿病并发症（-3.5 [-4.0 至 -2.9]，P < 0.001）与较低的身体 HRQL 相关。最低心理 HRQL 与抑郁、体重不足 (BMI <18 kg/m2)、截肢和低血糖有关。在组合暴露模型中，只有低血糖与较低的心理 HRQL 相关（−4.0 [−7.0 至 −1.1]，P = 0.008）。老年综合征和低血糖与较低的 HRQL 相关，其程度与糖尿病并发症相当。解决老年综合征和避免低血糖应与预防老年糖尿病患者的糖尿病并发症同等重要。
To evaluate associations between health-related quality of life (HRQL) and geriatric syndromes, diabetes complications, and hypoglycemia in older adults with diabetes. A race-stratified random sample of 6,317 adults with type 2 or type 1 diabetes, aged 60 to 75 years, enrolled in Kaiser Permanente Northern California, who completed a survey that included a HRQL instrument based on the Short Form 8-item health survey. Administrative records were used to ascertain diagnoses of geriatric syndromes, diabetes complications, and hypoglycemia. Associations were estimated between HRQL and exposures in exposure-specific and combined exposure models (any syndrome, any complication, or hypoglycemia). Conservatively, differences of ≥3 points were considered the minimally important difference in HRQL scores. HRQL was lower with nearly all exposures of interest. The lowest physical HRQL was associated with amputation. In combined exposure models, geriatric syndromes (−5.3 [95% CI −5.8 to −4.8], P < 0.001) and diabetes complications (−3.5 [−4.0 to −2.9], P < 0.001) were associated with lower physical HRQL. The lowest mental HRQL was associated with depression, underweight (BMI <18 kg/m2), amputation, and hypoglycemia. In combined exposure models, only hypoglycemia was associated with lower mental HRQL (−4.0 [−7.0 to −1.1], P = 0.008). Geriatric syndromes and hypoglycemia are associated with lower HRQL to a comparable degree as diabetes complications. Addressing geriatric syndromes and avoiding hypoglycemia should be given as high a priority as preventing diabetes complications in older adults with diabetes.
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影响因子：
3.5
作者：
Ware, JE;Kosinski, M
通讯作者：
Kosinski, M
影响因子：
3.6
作者：
Graham, James E.;Stoebner-May, Diane G.;Ottenbacher, Kenneth J.
通讯作者：
Ottenbacher, Kenneth J.
影响因子：
16.2
作者：
Krein, SL;Heisler, M;Kerr, EA
通讯作者：
Kerr, EA
影响因子：
3.5
作者：
Turner-Bowker, DM;Bayliss, MS;Kosinski, M
通讯作者：
Kosinski, M
影响因子：
158.5
作者：
Gerstein, Hertzel C.;Miller, Michael E.;Friedewald, William T.
通讯作者：
Friedewald, William T.