FeSO4-promoted direct arylation of benzoquinones with ArB(OH)2 or ArBF3K
FeSO4-promoted direct arylation of benzoquinones with ArB(OH)2 or ArBF3K
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DOI：
10.1016/j.tetlet.2012.12.031
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发表时间：
2013-02-27
影响因子：
1.8
通讯作者：
Takaki, Ken
中科院分区：
文献类型：
--
作者：
Komeyama, Kimihiro;Kashihara, Tetsuya;Takaki, Ken
在K_2S_2O_8存在下，FeSO_4中心点7H（2）O被证明是苯醌与芳基硼酸直接芳基化反应的有效促进剂。在芳基化反应中，缓慢加入铁溶液对反应的有效进行至关重要。有趣的是，铁介导的芳基化反应可以转化为催化反应，通过使用氢醌，而不是苯醌，或添加抗坏血酸。(C)2012爱思唯尔有限公司保留所有权利。
FeSO4 center dot 7H(2)O was proven to work as effective promoter for the direct arylation of benzoquinones with aryl boronic acids in the presence of K2S2O8. In the arylation, slow addition of iron solution was crucial to efficiently proceed with the reaction. Interestingly, the Fe-mediated arylation could be converted into a catalytic reaction by using hydroquinones, instead of benzoquinones, or addition of ascorbic acid. (C) 2012 Elsevier Ltd. All rights reserved.