Cadenza ad libitum: cGAS and STING showcase their versatile virtuosities in the Ca2+-dependent rescue of stalled replication forks.

Cadenza ad libitum: cGAS and STING showcase their versatile virtuosities in the Ca2+-dependent rescue of stalled replication forks.
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Cadenza ad libitum:cGAS 和 STING 展示了它们在 Ca2 依赖的停滞复制叉救援中的多才多艺。

DOI:
10.1016/j.molcel.2023.01.021
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发表时间:
2023
期刊:
影响因子:
16
通讯作者:
Sohn,Jungsan
Sohn,Jungsan
中科院分区:
生物学1区
文献类型:
--
作者:
Sohn,Jungsan

文献摘要

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在这一期的《分子细胞》杂志上,Li et al.报道cGAS-STING胞质dsDNA传感途径在调节TRPV 2钙通道以拯救复制叉中起关键作用。
In this issue ofMolecular Cell, Li et al. report that the cGAS-STING cytosolic dsDNA sensing pathway plays a crucial role in regulating the TRPV2 calcium channel to rescue replication forks.