Diet and uterine myomas

Diet and uterine myomas
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DOI:
10.1016/s0029-7844(99)00305-1
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发表时间:
1999-09-01
影响因子:
7.2
通讯作者:
Marsico, S
Marsico, S
中科院分区:
医学2区
文献类型:
--
作者:
Chiaffarino, F;Parazzini, F;Marsico, S

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目的:分析选定的饮食指标与子宫肌瘤风险之间的关系。方法:我们使用了 1986 年至 1997 年间在意大利进行的子宫肌瘤危险因素病例对照研究的数据。病例包括 843 名临床诊断不超过 2 年的子宫肌瘤女性。对照是 1557 名 55 岁以下、未接受子宫切除术、因急性非妇科、非激素、非肿瘤性疾病入院的女性。 结果:患有子宫肌瘤的女性报告更频繁地食用牛肉、其他红肉和火腿,而较少食用绿色蔬菜、水果和鱼类。上三分位的多变量比值比,牛肉和其他红肉为 1.7(95% 置信区间 [CI] 1.4, 2.2),火腿为 1.3(95% CI 1.0, 1.6),绿色蔬菜为 0.5(95% CI 0.4, 0.6),水果消费为 0.8(95% CI 0.6, 1.0).结论:肌瘤与牛肉和火腿的食用有关,而大量摄入绿色蔬菜似乎具有保护作用。 (C) 1999 年,美国妇产科医师学会。
Objective: To analyze the relation between selected dietary indicators and the risk of uterine myomas.Methods: We used data from a case-control study on risk factors for uterine myomas conducted in Italy between 1986 and 1997. Cases included 843 women with uterine myomas whose clinical diagnoses dated back no more than 2 years. Controls were 1557 women younger than age 55 who had not had hysterectomies and were admitted for acute nongynecologic, nonhormonal, nonneoplastic conditions.Results: Women with uterine myomas reported more frequent consumption of beef, other red meat, and ham and less frequent consumption of green vegetables, fruit, and fish. The multivariate odds ratios in the upper tertile were 1.7 for beef and other red meat (95% confidence interval [CI] 1.4, 2.2), 1.3 for ham (95% CI 1.0, 1.6), 0.5 for green vegetables (95% CI 0.4, 0.6), and 0.8 for fruit consumption (95% CI 0.6, 1.0).Conclusion: Myoma is associated with beef and ham consumption, whereas high intake of green vegetables seems to have a protective effect. (C) 1999 by The American College of Obstetricians and Gynecologists.