From Haeckel to event-pairing: the evolution of developmental sequences
From Haeckel to event-pairing: the evolution of developmental sequences
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DOI：
10.1007/s12064-002-0016-5
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发表时间：
2002-11-01
影响因子：
1.1
通讯作者：
Richardson, MK
中科院分区：
文献类型：
--
作者：
Bininda-Emonds, ORP;Jeffery, JE;Richardson, MK
发展涉及一系列发展事件，由转化分开，遵循特定的顺序或发展序列。该序列又可以被任意地细分为连续的片段（发育阶段）。我们讨论了发展序列的性质。我们还研究了不同的分析方法，已被用来分析在进化的背景下发展序列。Ernst Haeckel是这一领域的先驱。他的方法是进化的，他引入了序列异时性（在发育事件序列中的进化变化）的概念。尽管有详细的发展数据（E。G.虽然海克尔的《正常表》（Normal Tables）并没有对发育数据进行定量分析。现在，通过基于计算机的分析技术，如事件配对，这是可能的，它可以从发育序列中提取重要的生物信息，将它们映射到已建立的遗传学上。它还可能产生可用于系统发育重建的数据，尽管数据固有的“非独立性”可能使其无效。在未来，这里讨论的方法可能会被应用到胚胎中的基因表达模式的分析，或适用于研究染色体上的基因顺序。
Development involves a series of developmental events, separated by transformations, that follow a particular order or developmental sequence. The sequence may in turn be arbitrarily subdivided into contiguous segments (developmental stages). We discuss the properties of developmental sequences. We also examine the differing analytical approaches that have been used to analyse developmental sequences in an evolutionary context. Ernst Haeckel was a pioneer in this field. His approach was evolutionary and he introduced the idea of sequence heterochrony (evolutionary changes in the sequence of developmental events). Despite the availability of detailed developmental data (e. g. Franz Keibel's 'Normal Tables'), Haeckel was unable to undertake a quantitative analysis of developmental data. This is now possible through computer-based analytical techniques such as event-pairing, which can extract important biological information from developmental sequences by mapping them onto established phylogenies. It may also yield data that can be used in phylogeny reconstruction, although the inherent 'non-independence' of the data may make this invalid. In future, the methods discussed here may be applied to the analysis of patterns of gene expression in embryos, or adapted to studying gene order on chromosomes.