Dynamic concentration of motors in microtubule arrays
Dynamic concentration of motors in microtubule arrays
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DOI：
10.1103/physrevlett.86.3192
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发表时间：
2001-04-02
影响因子：
8.6
通讯作者：
Maggs, AC
中科院分区：
文献类型：
--
作者：
Nédélec, F;Surrey, T;Maggs, AC
我们介绍了微管阵列和ASTER中分子马达动力学的实验和理论研究。通过求解一个对流扩散方程，我们发现二维星体中电机的密度分布具有指数连续变化的特征。模拟结果被用来验证连续介质模型的假设。我们用荧光显微镜观察了运动蛋白在准二维人工植物中的浓度分布，并与我们的理论结果进行了比较。
We present experimental and theoretical studies of the dynamics of molecular motors in microtubule arrays and asters. By solving a convection-diffusion equation we find that the density profile of motors in a two-dimensional aster is characterized by continuously varying exponents. Simulations are used to verify the assumptions of the continuum model. We observe the concentration profiles of kinesin moving in quasi-two-dimensional artificial asters by fluorescent microscopy and compare with our theoretical results.