Diagnosis and treatment of small-bowel stricture by double balloon endoscopy

Diagnosis and treatment of small-bowel stricture by double balloon endoscopy
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DOI:
10.1016/j.gie.2007.02.027
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发表时间:
2007-09-01
影响因子:
7.7
通讯作者:
Sugano, Kentaro
Sugano, Kentaro
中科院分区:
医学1区
文献类型:
--
作者:
Fukumoto, Akira;Tanaka, Shinji;Sugano, Kentaro

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背景:小肠狭窄的来源往往难以诊断,因为难以将内窥镜置入小肠。最近,通过双气囊内镜(DBE)检查整个小肠并进行气囊扩张治疗狭窄已成为可能。目的:识别小肠狭窄的临床特征并确定气囊扩张作为治疗选择的有效性。设计:回顾性多中心研究。设置:DBE工作组下属7个机构的研究人员。患者:在7家机构接受DBE的1035例患者中,有179例狭窄患者。干预措施:根据临床指征进行手术治疗或球囊扩张。主要结果测量:通过DBE检测狭窄病变的能力、病变类型、小肠狭窄的位置、狭窄的细节、狭窄的治疗,结果:179例狭窄患者中,179例狭窄患者中。在156例患者的小肠内检测到病变。炎症性疾病是小肠狭窄患者中最常见的(n = 87),回肠是炎症性疾病最常见的部位。克罗恩病是最常见的炎症性疾病(n = 57)。在31例炎症性疾病患者中进行了球囊扩张,并在22 patients.Limitations取得了长期的成功:治疗的患者人数由球囊扩张small.Conclusion:DBE似乎是有用的检测以及治疗小肠病变。
Background: The source of small-bowel stricture is often difficult to diagnose due to the difficulty, of placing an endoscope into the small bowel. It has recently become possible to examine the entire small bowel and perform balloon dilatation for stricture by means of double balloon endoscopy (DBE).Objective: To identify clinical features of small-bowel stricture and determine the validity of balloon dilatation as a treatment option.Design: Retrospective multicenter study.Setting: Researchers at 7 institutions affiliated with the DBE Working Group.Patients: One hundred seventy-nine patients with stricture among a total of 1035 patients who underwent DBE at the 7 institutions.Interventions: Surgical treatment or balloon dilatation was performed as clinically indicated.Main Outcome Measurements: Ability to detect stricture lesions by DBE, types of lesions, locations of small-bowel strictures, details of strictures, treatments for strictures, and outcomes of balloon dilatation for strictures associated with inflammatory disease.Results: The total number of patients with strictures was 179. Lesions were detected within the small bowel in 156 patients. Inflammatory disease was the most common (n = 87) in patients with small-bowel stricture, and the ileum was the most common site of the inflammatory disease. Crohn's disease was the most common of the inflammatory diseases (n = 57). Balloon dilatations were performed in 31 patients with inflammatory disease, and long-term success was achieved in 22 patients.Limitations: The number of patients treated by balloon dilatation was small.Conclusion: DBE appears to be useful for the detection as well as treatment of small-bowel lesions.