Schistosomiasis of the spinal cord
Schistosomiasis of the spinal cord
复制标题
脊髓血吸虫病
作者：
R. Lechtenberg;G. Vaida
文章摘要4例脊髓血吸虫病的特点是下肢轻瘫，感觉丧失，括约肌功能障碍进展数小时至数天。1例患者在椎板切除术后数月内出现恶化和缓解，随后出现典型的快速进展性缺陷。2例患者活检显示肉芽肿和坏死性肌病。尽管进行了化疗，但自发的改善和持续的恶化使治疗的评估变得困难。对所有先前报告的病例进行的调查没有提供对任何治疗方式的一致反应模式。椎板切除术减压和诊断，管理抗肿瘤药物，和高剂量口服强的松在疾病的早期建议。
Article abstract Four cases of spinal cord schistosomiasis were characterized by paraparesis, sensory loss, and sphincter disturbances progressing over hours to days. One patient showed deterioration over months and remissim after laminectomy, followed by the typical, rapidly progressive deficits. Biopsies on two patients showed granulomatous and necrotizing myelitis. Spontaneous improvement and unremitting deterioration, despite chemotherapy, make evaluation of treatment difficult. A survey of all previously reported cases provided no consistent pattern of response to any treatment modalities. Laminectomy for decompression and diagnosis, administration of antischistosomal medications, and high-dose oral prednisone early in the illness are recommended.