Increasing Utilization of Allogeneic Bone Marrow Transplantation

Increasing Utilization of Allogeneic Bone Marrow Transplantation
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提高同种异体骨髓移植的利用率

DOI:
--
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发表时间:
1992
影响因子:
39.2
通讯作者:
A. Rimm
A. Rimm
中科院分区:
医学1区
文献类型:
--
作者:
M. Bortin;M. Horowitz;A. Rimm

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目的 确定1988年至1990年间来自亲缘和非亲缘供者的异基因骨髓移植的模式和频率。 设计和设置 对47个国家的342个机构进行了调查。 测量 在具有活跃的异基因骨髓移植项目的机构中接受骨髓移植治疗特定疾病类别的患者数量。 主要结果 1988年至1990年间,患者(14,745例)接受了异基因骨髓移植;其中,1153例(8%)来自无关供体。移植的原因是急性白血病(47%),慢性粒细胞白血病(27%),淋巴瘤和其他恶性肿瘤(10%),严重再生障碍性贫血(9%),和其他非恶性疾病(7%)。每百万人中异基因骨髓移植的数量因国家而异,北美平均为每百万人7.7例,西欧为每百万人5.7例。 结论 异基因骨髓移植的使用继续以每年增加600多名患者和25个新的移植团队的速度增加。这一增加的部分原因是越来越多地使用无关的志愿者作为捐助者。各国为移植分配的资源差别很大。
OBJECTIVE To determine the pattern and frequency of allogeneic bone marrow transplantation from related and unrelated donors from 1988 to 1990. DESIGN AND SETTING Survey of 342 institutions in 47 countries. MEASUREMENTS Numbers of patients receiving bone marrow transplantation for specific disease categories at institutions with active allogeneic bone marrow transplant programs. MAIN RESULTS Patients (14,745) received allogeneic bone marrow transplantation between 1988 and 1990; of these, 1153 (8%) were from unrelated donors. Reasons for transplantation were acute leukemia (47%), chronic myelogenous leukemia (27%), lymphoma and other malignancies (10%), severe aplastic anemia (9%), and other nonmalignant diseases (7%). The number of allogeneic bone marrow transplants per million persons differed among countries, averaging 7.7 per million in North America and 5.7 per million in western Europe. CONCLUSIONS The use of allogeneic bone marrow transplantation continued to increase at a rate of more than 600 additional patients and 25 new transplant teams annually. This rise is due in part to increasing use of unrelated volunteers as donors. Resources allocated for transplants vary widely among countries.
更昔洛韦/免疫球蛋白联合疗法用于治疗骨髓同种异体移植受者中人巨细胞病毒相关的间质性肺炎。
DOI: --
发表时间: 1988
期刊: Transplantation
影响因子: 6.2
作者:
Schmidt,GM;Kovacs,A;Zaia,JA;Horak,DA;Blume,KG;Nademanee,AP;O'Donnell,MR;Snyder,DS;Forman,SJ
通讯作者: Forman,SJ
DOI: --
发表时间: 1989
影响因子: 4.8
作者:
Beatty,PG;Ash,R;Hows,JM;McGlave,PB
通讯作者: McGlave,PB
DOI: --
发表时间: 1991-06
影响因子: 4.8
作者:
R. Ash;M. Horowitz;R. Gale;D. Bekkum;J. Casper;E. Gordon-Smith;P. Henslee;H. Kolb;B. Lowenberg-B
通讯作者: R. Ash;M. Horowitz;R. Gale;D. Bekkum;J. Casper;E. Gordon-Smith;P. Henslee;H. Kolb;B. Lowenberg-B
DOI: 10.1097/00007890-198609000-00001
发表时间: 1986
期刊: Transplantation
影响因子: 6.2
作者:
Bortin,MM;Rimm,AA
通讯作者: Rimm,AA
DOI: 10.1056/nejm198603203141201
发表时间: 1986-03-20
影响因子: 158.5
作者:
STORB, R;DEEG, HJ;THOMAS, ED
通讯作者: THOMAS, ED