Human plasma concentrations of cytochrome P450 probe cocktails extrapolated from pharmacokinetics in mice transplanted with human hepatocytes and from pharmacokinetics in common marmosets using physiologically based pharmacokinetic modeling

Human plasma concentrations of cytochrome P450 probe cocktails extrapolated from pharmacokinetics in mice transplanted with human hepatocytes and from pharmacokinetics in common marmosets using physiologically based pharmacokinetic modeling
复制标题

使用基于生理学的药代动力学模型,根据移植人肝细胞的小鼠的药代动力学和普通狨猴的药代动力学推断出细胞色素 P450 探针混合物的人血浆浓度

DOI:
10.3109/00498254.2016.1147102
复制
发表时间:
2015
期刊:
影响因子:
1.8
通讯作者:
H.
H.
中科院分区:
医学4区
文献类型:
--
作者:
Utoh;M.;Suemizu;H.;Mitsui;M.;Kawao;M.;Toda;A.;Uehara;S.;Uno;Y.;Shimizu;M.;Sasaki;E.;and Yamazaki;H.

文献摘要

相似文献