Cost-effectiveness Analysis of Nutrition Facts Added-Sugar Labeling and Obesity-Associated Cancer Rates in the US.
Cost-effectiveness Analysis of Nutrition Facts Added-Sugar Labeling and Obesity-Associated Cancer Rates in the US.
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DOI：
10.1001/jamanetworkopen.2021.7501
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发表时间：
2021-04-01
影响因子：
13.8
通讯作者：
Food-PRICE Project
中科院分区：
文献类型：
--
作者：
Du M;Griecci CF;Cudhea FF;Eom H;Kim DD;Wilde P;Wong JB;Wang YC;Michaud DS;Mozaffarian D;Zhang F;Food-PRICE Project
在美国，添加糖标签和肥胖相关癌症发病率之间的估计关联是什么？这项对营养成分添加糖标签和肥胖相关癌症发病率的经济评估估计，实施该政策与美国成年人一生中减少30，000例新发癌症病例，17，100例癌症死亡和16亿美元的医疗费用有关。这项政策将从社会角度产生7.04亿美元的净节省，从保健角度产生15.9亿美元的净节省。这些模型研究结果表明，添加糖的标签将与降低成本和降低肥胖相关癌症的发病率有关。在美国，与肥胖相关的癌症负担正在增加。营养政策，如添加糖的营养成分标签，可能会降低肥胖相关的癌症发病率。评估美国营养成分添加糖标签和肥胖相关癌症发病率的成本效益。使用概率队列状态转换模型对2.35亿年龄在20岁或以上的成年人中的添加糖标签和13种肥胖相关癌症进行经济评估，按年龄，性别和种族/种族进行中位随访34.4年。政策协会被认为是在2种情况下：与消费者的行为和额外的行业重新制定。该模型整合了全国代表性的人口统计数据，饮食和癌症统计数据;政策干预与饮食，饮食变化和身体质量指数以及身体质量指数与癌症风险的关联;以及来自既定来源的政策和健康相关成本。数据分析时间为2019年1月8日至2020年5月6日。从社会和卫生保健的角度估计净成本和增量成本-效果比。概率敏感性分析纳入了输入参数的不确定性，并生成了95%的不确定性区间（UI）。根据消费者的行为，该政策与减少30 000（95% UI，21 600-39 300）新癌症病例和17 100（95% UI，12 400-22 700）癌症死亡，增加116 000（95% UI，83 800-153 000）质量调整生命年，并节省16亿美元（95% UI，11.9亿美元-20.3亿美元）的医疗费用与癌症护理在美国成年人的一生。该政策从社会角度节省了7.04亿美元（95% UI，4450万美元-14.5亿美元），从医疗保健角度节省了15.9亿美元（95% UI，11.8亿美元-20.2亿美元）。另外的行业重新制定，以减少包装食品和饮料中的添加糖量将使影响加倍。预计年轻人、妇女和非西班牙裔黑人的健康收益和成本节省将高于其他人群。这些发现表明，添加糖的标签与降低成本和降低肥胖相关癌症的发病率有关。政策制定者可能会考虑并优先考虑美国预防癌症的营养政策。这项经济评估从社会和医疗保健的角度研究了美国食品添加糖标签的使用与癌症发病率之间的关系。
What is the estimated association between added-sugar labeling and obesity-related cancer rates in the US? This economic evaluation of Nutrition Facts added-sugar labeling and obesity-related cancer rates estimated that implementing the policy was associated with a reduction of 30 000 new cancer cases, 17 100 cancer deaths, and $1600 million in medical costs among US adults over a lifetime. This policy would generate net savings of $704 million from a societal perspective and $1590 million from a health care perspective. These model findings suggest added-sugar labeling would be associated with reduced costs and lower rates of obesity-related cancers. Obesity-associated cancer burdens are increasing in the US. Nutrition policies, such as the Nutrition Facts added-sugar labeling, may reduce obesity-associated cancer rates. To evaluate the cost-effectiveness of Nutrition Facts added-sugar labeling and obesity-associated cancer rates in the US. A probabilistic cohort state-transition model was used to conduct an economic evaluation of added-sugar labeling and 13 obesity-associated cancers among 235 million adults aged 20 years or older by age, sex, and race/ethnicity over a median follow-up of 34.4 years. Policy associations were considered in 2 scenarios: with consumer behaviors and with additional industry reformulation. The model integrated nationally representative population demographics, diet, and cancer statistics; associations of policy intervention with diet, diet change and body mass index, and body mass index with cancer risk; and policy and health-related costs from established sources. Data were analyzed from January 8, 2019, to May 6, 2020. Net costs and incremental cost-effectiveness ratio were estimated from societal and health care perspectives. Probabilistic sensitivity analyses incorporated uncertainty in input parameters and generated 95% uncertainty intervals (UIs). Based on consumer behaviors, the policy was associated with a reduction of 30 000 (95% UI, 21 600-39 300) new cancer cases and 17 100 (95% UI, 12 400-22 700) cancer deaths, a gain of 116 000 (95% UI, 83 800-153 000) quality-adjusted life-years, and a saving of $1600 million (95% UI, $1190 million-$2030 million) in medical costs associated with cancer care among US adults over a lifetime. The policy was associated with a savings of $704 million (95% UI, $44.5 million-$1450 million) from the societal perspective and $1590 million (95% UI, $1180 million-$2020 million) from the health care perspective. Additional industry reformulation to reduce added-sugar amounts in packaged foods and beverages would double the impact. Greater health gains and cost savings were expected among young adults, women, and non-Hispanic Black individuals than other population subgroups. These findings suggest that the added-sugar labeling is associated with reduced costs and lower rates of obesity-associated cancers. Policymakers may consider and prioritize nutrition policies for cancer prevention in the US. This economic evaluation examines the association between the use of added-sugar labeling of food products in the US and the incidence of cancer from societal and health care perspectives.
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影响因子：
37.8
作者：
Huang, Yue;Kypridemos, Chris;Micha, Renata
通讯作者：
Micha, Renata
影响因子：
4.5
作者：
Shih, Ya-Chen Tina;Dong, Wenli;Shen, Yu
通讯作者：
Shen, Yu
影响因子：
2.6
作者：
Machin, Leandro;Cabrera, Manuel;Ares, Gaston
通讯作者：
Ares, Gaston
影响因子：
2.3
作者：
Nogueira, Leticia M.;Thai, Chan L.;Oh, April
通讯作者：
Oh, April
DOI：
10.1056/nejmoa1014296
发表时间：
2011-06-23
期刊：
The New England journal of medicine
影响因子：
--
作者：
Mozaffarian D;Hao T;Rimm EB;Willett WC;Hu FB
通讯作者：
Hu FB