Association of Central Versus Brachial Blood Pressure With Target-Organ Damage Systematic Review and Meta-Analysis
Association of Central Versus Brachial Blood Pressure With Target-Organ Damage Systematic Review and Meta-Analysis
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DOI：
10.1161/hypertensionaha.115.06066
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发表时间：
2016-01-01
期刊：
影响因子：
8.3
通讯作者：
Stergiou, George S.
中科院分区：
文献类型：
--
作者：
Kollias, Anastasios;Lagou, Styliani;Stergiou, George S.
越来越多的证据表明，中心血压(BP)可以比臂部血压更准确地反映靶器官的血流动力学应激。我们进行了一项系统的综述，评估了中心血压和臂动脉血压与临床前靶器官损害的关系。横断面数据的Meta分析显示，与臂部收缩压相比，中心性收缩压与(1)左心室重量指数(12项研究，n=6431；加权年龄[SD]，49.9[13.1]岁；51%高血压患者)关系更为密切：合并相关系数r=0.30；95%可信区间(CI)0.23~0.37对r=0.26；95%CI分别为0.19~0.33；P
Accumulating evidence suggests that central blood pressure (BP) may reflect the hemodynamic stress on target organs more accurately than brachial BP. A systematic review assessing the relationship of central versus brachial BP with preclinical target-organ damage was performed. Meta-analysis of cross-sectional data showed that central compared with brachial systolic BP was more closely associated with (1) left ventricular mass index (12 studies, n=6431; weighted age [SD], 49.9 [13.1] years; 51% hypertensives): pooled correlation coefficients r=0.30; 95% confidence interval (CI), 0.23-0.37 versus r=0.26; 95% CI, 0.19-0.33, respectively; P