STRUCTURAL DIVERSITY OF MARGINAL (LAMINA-I) NEURONS IN THE ADULT MONKEY (MACACA-MULATTA) LUMBOSACRAL SPINAL-CORD - A GOLGI-STUDY
STRUCTURAL DIVERSITY OF MARGINAL (LAMINA-I) NEURONS IN THE ADULT MONKEY (MACACA-MULATTA) LUMBOSACRAL SPINAL-CORD - A GOLGI-STUDY
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DOI：
10.1002/cne.902020209
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发表时间：
1981-01-01
影响因子：
2.5
通讯作者：
BICKNELL, HR
中科院分区：
文献类型：
--
作者：
BEAL, JA;PENNY, JE;BICKNELL, HR
利用高尔基体技术，对灵长类动物进行了结构分析[M. mulatta]边缘（板I）神经元在腰骶脊髓。边缘神经元是根据树突的形态、分布和特化的主要结构差异进行分类的。细胞大小和形状本身不是可靠的标准。边缘细胞可分为4大类。组I（具有厚的钝树突的有刺神经元）由具有相对厚的树突的神经元组成，所述树突具有突然的钝的终止和很少的刺。这种异质组包括各种形状的大、中、小神经元。第II组细胞（大到中等多刺神经元）可以细分为2个不同的组：第IIA组神经元，其具有纵向多刺树突状乔木，和第IIB组细胞，其具有中等多刺的扇形树突状乔木，其分布在背侧边缘区的外侧部分。A组和B组都显示出几种类型的棘。III族（具有细的锥形树突的多刺神经元）由小到中等大小的神经元组成，其可进一步分为2组：IIIA组，其特征在于具有在背外侧束和外侧索中分叉的曲折、细、锥形树突的卵圆形至梭形神经元，和IIIB组，其由梭形、锥体形和漏斗形神经元组成，锥形树突局限于第一层。第IV组（小棘神经元）的特征是小梭形至椭圆形的细胞体和精致的纵向树突，树突上有小的短颈有蒂的棘。该组被细分为IVA组细胞和IVB组细胞，IVA组细胞位于板层I内，IVB组细胞位于背外侧束中，具有无髓鞘轴突。边缘带内的结构多样性比以前报道的要多得多。提供足够的变化与功能差异描述的I层神经元。
Utilizing the Golgi technique, a structural analysis was made of primate [M. mulatta] marginal (lamina I) neurons in the lumbrosacral spinal cord. Marginal neurons are classified on the basis of major structural differences in dendritic conformation, distribution and specialization. Cell size and shape alone were not reliable criteria. Marginal cells can be divided into 4 major groups. Group I (aspiny neurons with thick, blunt dendrites) consists of neurons with relatively thick dendrites which have an abrupt, blunt termination and few spines. This heterogeneous group includes large, medium and small neurons of various shapes. Group II cells (large to medium spiny neurons) can be subdivided into 2 distinct groups: group IIA neurons, which have longitudinal spiny dendritic arbors, and group IIB cells, which have a moderately spiny, fan-shaped dendritic arbor which spreads across the lateral portion of the dorsal marginal zone. Both groups A and B exhibit several types of spines. Group III (aspiny neurons with thin, tapering dendrites) consists of small to medium size neurons which can be further divided into 2 groups: group IIIA, which is characterized by oval- to fusiform-shaped neurons with tortuous, fine, tapered dendrites which ramify in the dorsolateral fasciculus and the lateral funiculus, and group IIIB, which is composed of fusiform-, pyramidal- and polygonal-shaped neurons with fine, tapering dendrites confined to lamina I. Group IV (small spiny neurons) are characterized by a small fusiform- to pyramidal-shaped cell body and delicate longitudinal dendrites with small, short-necked pedunculated spines. This group is subdivided into group IVA cells, which are found within lamina I proper and group IVB cells, which are located in the dorsolateral fasciculus and have unmyelinated axons. There is considerably more structural diversity within the marginal zone than was previously reported. Sufficient variation is offered to correlate with functional differences described for lamina I neurons.