Improved Estimation of Coronary Plaque and Luminal Attenuation Using a Vendor-specific Model-based Iterative Reconstruction Algorithm in Contrast-enhanced CT Coronary Angiography.

Improved Estimation of Coronary Plaque and Luminal Attenuation Using a Vendor-specific Model-based Iterative Reconstruction Algorithm in Contrast-enhanced CT Coronary Angiography.
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DOI:
10.1016/j.acra.2017.02.006
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发表时间:
2017-09
期刊:
影响因子:
4.8
通讯作者:
Yamashita Y
Yamashita Y
中科院分区:
医学3区
文献类型:
--
作者:
Funama Y;Utsunomiya D;Hirata K;Taguchi K;Nakaura T;Oda S;Kidoh M;Yuki H;Yamashita Y

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通过冠状动脉CT血管成像,研究不同斑块类型、狭窄程度、管腔密度和重建方法对冠状动脉斑块衰减和管腔稳定性的影响。我们使用三种类型的斑块CT编号对狭窄的血管管和无狭窄的血管管进行320探测器容积扫描。狭窄程度分别为50%和75%。采用滤波反投影(FBP)和两种类型的迭代重建(AIDR 3D和FIRST)重建图像,狭窄CT数分别约为40、80和150 HU。在每种情况下,冠状动脉血管的管路均填充有稀释的造影剂和蒸馏水,以分别达到约350 HU和450 HU以及0 HU的目标管腔CT值。测量峰值管腔和斑块CT数以计算管腔-斑块对比度。此外,我们回顾性评价了图像质量方面的冠状动脉管腔和斑块在10个临床患者的四点量表。在50%狭窄时,对于FBP和AIDR 3D,造影增强的斑块CT数量增加,对于FBP和AIDR 3D,造影增强和非造影增强的斑块CT数量差异为15-44 HU和10-31 HU。然而,FIRST的斑块CT数变化较小,有和无造影剂增强的差异为-12-8 HU。对于FBP、AIDR 3D和FIRST,血管腔的视觉评价评分分别为2.8 ± 0.6、3.5 ± 0.5和3.7 ± 0.5。FIRST方法控制斑块密度和管腔-斑块对比度的增加。因此,它改善了冠状动脉CT血管造影中冠状动脉斑块的可视化。
To investigate the stabilities of plaque attenuation and coronary lumen for different plaque types, stenotic degrees, lumen densities, and reconstruction methods using coronary vessel phantoms and the visualization of coronary plaques in clinical patients through coronary CT angiography. We performed 320-detector volume scanning of vessel tubes with stenosis and a tube without stenosis using three types of plaque CT numbers. The stenotic degrees were 50% and 75%. Images were reconstructed with filtered back projection (FBP) and two types of iterative reconstructions (AIDR3D and FIRST), with stenotic CT number of approximately 40, 80, and 150 HU, respectively. In each case, the tubing of the coronary vessel was filled with diluted contrast material and distilled water to reach the target lumen CT numbers of approximately 350 HU and 450 HU, and 0 HU, respectively. Peak lumen and plaque CT numbers were measured to calculate the lumen–plaque contrast. In addition, we retrospectively evaluated the image quality with regard to coronary arterial lumen and the plaque in ten clinical patients on a four-point scale. At 50% stenosis, the plaque CT number with contrast enhancement increased for FBP and AIDR3D and the difference in the plaque CT number with and without contrast enhancement was 15–44 HU for FBP and 10–31 HU for AIDR3D. However, the plaque CT number for FIRST had a smaller variation and the difference with and without contrast enhancement was −12–8 HU. The visual evaluation score for the vessel lumen was 2.8 ± 0.6, 3.5 ± 0.5, and 3.7 ± 0.5 for FBP, AIDR3D, and FIRST, respectively. The FIRST method controls the increase in plaque density and the lumen–plaque contrast. Consequently, it improves the visualization of coronary plaques in coronary CT angiography.
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