Traditional Risk Factors of Acute Coronary Syndrome in Four Different Male Populations - Total Cholesterol Value Does Not Seem To Be Relevant Risk Factor
Traditional Risk Factors of Acute Coronary Syndrome in Four Different Male Populations - Total Cholesterol Value Does Not Seem To Be Relevant Risk Factor
复制标题
DOI：
10.33549/physiolres.933597
复制
发表时间：
2017-01-01
影响因子：
2.1
通讯作者：
Pitha, J.
中科院分区：
文献类型：
--
作者：
Hubacek, J. A.;Stanek, V.;Pitha, J.
在大多数人口中，心血管疾病是最常见的死亡和发病原因。由于传统的可改变的危险因素(吸烟、高血压、血脂异常、糖尿病和肥胖)在几十年前就被定义，我们决定分析急性冠脉综合征(ACS)存活患者的最新数据。捷克部分的研究包括了999名男性的数据，并将他们与莫妮卡之后的研究(1259名男性，代表普通人群)进行了比较。立陶宛的这项研究包括479名男性患者和456名年龄匹配的对照组。哈萨克斯坦部分包括232名患者和413名对照。在两个国家，最明显的急性冠脉综合征危险因素是吸烟(在捷克研究中为3.85，在立陶宛研究中为5.76)，其次是糖尿病(OR2.26和2.07)和高血压(中度风险升高，OR1.43和1.49)。这些因素并不影响哈萨克斯坦的急性冠脉综合征风险。体重指数对急性冠脉综合征无明显影响，而血浆胆固醇水平显著降低(P
Cardiovascular diseases are the most common cause of mortality and morbidity in most populations. As the traditional modifiable risk factors (smoking, hypertension, dyslipidemia, diabetes mellitus, and obesity) were defined decades ago, we decided to analyze recent data in patients who survived acute coronary syndrome (ACS). The Czech part of the study included data from 999 males, and compared them with the post-MONICA study (1,259 males, representing general population). The Lithuanian study included 479 male patients and 456 age-matched controls. The Kazakhstan part included 232 patients and 413 controls. In two countries, the most robust ACS risk factor was smoking (OR 3.85 in the Czech study and 5.76 in the Lithuanian study), followed by diabetes (OR 2.26 and 2.07) and hypertension (moderate risk elevation with OR 1.43 and 1.49). These factors did not influence the ACS risk in Kazakhstan. BMI had no significant effect on ACS and plasma cholesterol was surprisingly significantly lower (P