RHO gene products, putative small GTP‐binding proteins, are importnat for activation of the CAL1/CDC43 gene product, a protein geranylgeranyltransferase in Saccharomyces cerevisiae
RHO gene products, putative small GTP‐binding proteins, are importnat for activation of the CAL1/CDC43 gene product, a protein geranylgeranyltransferase in Saccharomyces cerevisiae
复制标题
RHO 基因产物(假定的小 GTP 结合蛋白)对于 CAL1/CDC43 基因产物(酿酒酵母中的一种蛋白质香叶基香叶基转移酶)的激活非常重要
作者:
H. Qadota;I. Ishii;A. Fujiyama;Y. Ohya;Y. Anraku
Two multicopy suppressors of the call‐1 mutation in the yeast Saccharomyces cerevisiae have been isolated and characterized. They are identical to the yeast RHO1 and RHO2 genes, which encode putative small GTP‐binding proteins. Multiple copies of either RHO gene suppressed temperature‐sensitive growth of the call‐1 mutant but did not suppress the call null mutant. Genetic analysis suggests that overproduction of either RHO gene product acts for activation of the CAL1 gene product.
DOI:
10.1073/pnas.88.1.286
发表时间:
1991
影响因子:
11.1
作者:
Yamane,HK;Farnsworth,CC;Xie,HY;Evans,T;Howald,WN;Gelb,MH;Glomset,JA;Clarke,S;Fung,BK
通讯作者:
Fung,BK
DOI:
--
发表时间:
1991
期刊:
The Journal of biological chemistry
影响因子:
--
作者:
Ohya,Y;Goebl,M;Goodman,LE;Petersen-Bjørn,S;Friesen,JD;Tamanoi,F;Anraku,Y
通讯作者:
Anraku,Y