Deterioration of multifocal motor neuropathy after plasma exchange
Deterioration of multifocal motor neuropathy after plasma exchange
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DOI：
10.1212/wnl.50.5.1480
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发表时间：
1998-05-01
期刊：
影响因子：
9.9
通讯作者：
Nobile-Orazio, E
中科院分区：
文献类型：
--
作者：
Carpo, M;Cappellari, A;Nobile-Orazio, E
我们报告一位运动神经病患者，在血浆置换(PE)后，临床表现明显恶化，先前未受影响的运动神经出现传导阻滞，导致诊断为多灶性运动神经病(MMN)。这份报告强调了MMN和慢性炎症性脱髓鞘多神经病(CIDP)治疗的不同反应，因为不仅类固醇，而且PE，通常对CIDP有效，但没有改善，有时甚至可能恶化MMN。
We report a patient with motor neuropathy in whom plasma exchange (PE) was followed by a pronounced clinical worsening with the appearance of conduction blocks in previously clinically unaffected motor nerves, leading to the diagnosis of multifocal motor neuropathy (MMN). This report highlights the different response to therapy of MMN and chronic inflammatory demyelinating polyneuropathy (CIDP) because not only steroids but also PE, which is often effective in CIDP, do not improve and at times may even worsen MMN.