Breastfeeding in Infancy in Relation to Subsequent Physical Size: A 20-year Follow-up of the Ibaraki Children's Cohort Study (IBACHIL).
Breastfeeding in Infancy in Relation to Subsequent Physical Size: A 20-year Follow-up of the Ibaraki Children's Cohort Study (IBACHIL).
复制标题
婴儿期与随后的身体大小有关：伊巴拉基儿童队列研究（Ibachil）的20年随访。
DOI：
10.2188/jea.je20200562
复制
发表时间：
2023-02-05
影响因子：
4.7
通讯作者：
Ota, Hitoshi
中科院分区：
文献类型：
--
作者：
Sata, Mizuki;Yamagishi, Kazumasa;Sairenchi, Toshimi;Irie, Fujiko;Sunou, Keiko;Watanabe, Hiroshi;Iso, Hiroyasu;Ota, Hitoshi
据说母乳喂养可以预防儿童期超重和肥胖，但关于母乳喂养对青春期和成年期体型的长期影响的证据却很少。我们试图研究喂养类型与 3、6、12 和 22 岁时身体尺寸之间的关系。茨城儿童队列 (IBACHIL) 研究始于 1992 年，涉及来自一个县 87 个社区的 4,592 名日本儿童，他们的父母在孩子 3 岁时回答了有关孩子健康和生活习惯的健康调查问卷。当同一队列的 6 岁、12 岁和 22 岁时，我们向他们发放了后续调查问卷。根据喂养类型（母乳喂养、配方奶喂养和混合喂养）比较 3 岁（n = 4,290）、6 岁（n = 1,999；分析参与者比例 = 47%）、12 岁（n = 2,227；52%）和 22 岁（n = 1,459；34%）时自我报告的身高和体重、体重指数 (BMI) 和超重状况在婴儿期。 3 岁时，母乳喂养儿童的多变量调整平均体重和超重发生率均低于配方奶喂养儿童，男孩（体重：14.6 公斤 vs 14.7 公斤，P = 0.07，超重：6.3% vs 9.3%，P = 0.03）和女孩（14.0 公斤 vs 14.2 公斤，P = 0.01 和 10.4%） 13.6%，P = 0.06）。然而，根据喂养类型，6岁、12岁和22岁的体重、BMI和超重没有统计学上的显着差异。母乳喂养可以防止儿童时期超重，但其影响在青春期和成年期并不显着。
Breastfeeding is said to prevent overweight and obesity in childhood but the evidence about its long-term impact on body size into adolescence and adulthood is scarce. We sought to examine the association between feeding types and subsequent physical size at the ages of 3, 6, 12, and 22 years. The Ibaraki Children’s Cohort (IBACHIL) Study, which began in 1992, involved a cohort of 4,592 Japanese children from 87 communities of a single prefecture whose parents answered health questionnaires about their child’s health and life habits at the age of 3 years. Follow-up questionnaires were distributed to the same cohort when they were 6, 12, and 22 years old. Self-reported height and weight, body mass index (BMI), and overweight status at ages of 3 (n = 4,290), 6 (n = 1,999; proportion of participants analyzed = 47%), 12 (n = 2,227; 52%), and 22 (n = 1,459; 34%) years were compared according to feeding type (breastfeeding, formula feeding, and mixed feeding) during infancy. At the age of 3 years, multivariable adjusted-mean weight and prevalence of overweight were less for breastfed children than those formula-fed in both boys (weight: 14.6 kg vs 14.7 kg, P = 0.07, overweight: 6.3% vs 9.3%, P = 0.03) and in girls (14.0 kg vs 14.2 kg, P = 0.01 and 10.4% vs 13.6%, P = 0.06). However, there were no statistically significant differences in weight, BMI, and overweight at the ages of 6, 12, and 22 years according to feeding type. Breastfeeding may prevent overweight in childhood, but its impact is not significant in adolescence and adulthood.