Dentigerous cyst: a retrospective clinicopathological analysis of 2082 dentigerous cysts in British Columbia, Canada
Dentigerous cyst: a retrospective clinicopathological analysis of 2082 dentigerous cysts in British Columbia, Canada
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DOI：
10.1016/j.ijom.2010.04.048
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发表时间：
2010-09-01
影响因子：
2.4
通讯作者：
Poh, C. F.
中科院分区：
文献类型：
--
作者：
Zhang, L. L.;Yang, R.;Poh, C. F.
本研究的目的是分析含牙囊肿（DC）在加拿大不列颠哥伦比亚省人群队列中的患病率，并报告与DC相关的不寻常病例。检索了1998年至2007年期间的不列颠哥伦比亚省口腔活检服务数据库。从2029例患者中检索到2082例组织学证实的DC，并回顾性分析其发病率、年龄、性别和种族。结果表明，这是一种常见的颌骨囊肿，男性好发，在年轻人中发病率最高，在白人中更常见。多发性树突状细胞占病例的2.5%，与任何综合征或全身性疾病无关。0.5%的DC与颌骨同一部位或对侧的其他囊肿或肿瘤相关。作者报告了第一组临床表现为双侧树突状细胞，但组织学表现为牙源性肿瘤或另一种类型的牙源性囊肿的病例。树突状细胞可以与其他更严重的疾病共存，如牙源性角化囊肿或囊性成釉细胞瘤。这种与更重要的条件相关联表明组织学确认任何颌骨囊肿的重要性，即使它在临床上表现为典型的DC。
The aim of this research is to analyze the prevalence of dentigerous cysts (DCs) in a population-based cohort in British Columbia, Canada, and to report unusual cases associated with DC. The database of the British Columbia Oral Biopsy Service was searched from 1998 to 2007. 2082 histologically confirmed DCs from 2029 patients were retrieved and retrospectively analyzed for incidence, age, gender and ethnicity. The results show that this is a common jaw cyst with male predilection, has a peak incidence in younger adults and is more common in Caucasians. Multiple DCs, representing 2.5% of the cases, are not associated with any syndromes or systemic conditions. 0.5% DCs were associated with other cysts or tumours at the same site or the opposite side of the jaw. The authors report the first series of cases presenting clinically as bilateral DCs, but histologically as an odontogenic tumour or another type of odontogenic cyst. DCs can co-exist with other more serious conditions, such as odontogenic keratocyst or cystic ameloblastoma. This association with more significant conditions indicates the importance of histologically confirming any jaw cyst, even when it presents clinically as a classic DC.