Natural products for pest control: an analysis of their role, value and future
Natural products for pest control: an analysis of their role, value and future
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DOI：
10.1002/ps.3744
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发表时间：
2014-08-01
影响因子：
4.1
通讯作者：
Sparks, Thomas C.
中科院分区：
文献类型：
--
作者：
Gerwick, B. Clifford;Sparks, Thomas C.
天然产物（NP）长期以来一直被用作杀虫剂，并广泛用作当今市场上许多商业合成有机杀真菌剂，除草剂和杀虫剂的灵感来源。鉴于持续需要新的工具来解决不断变化的真菌、杂草和昆虫害虫，NP仍然是开发新害虫控制剂的模型和模板的来源。有趣的是，对文献的研究表明，NP模型存在于许多通过其他手段发现的害虫控制剂中，这表明，如果情况不同，这些NP可以作为发现更多当今害虫控制剂的灵感。在这里，试图回答的问题，现有的农药类的NP模型的存在和什么是需要为发现新的NP和NP模型的害虫控制剂。(C)2014年化学工业协会
Natural products (NPs) have long been used as pesticides and have broadly served as a source of inspiration for a great many commercial synthetic organic fungicides, herbicides and insecticides that are in the market today. In light of the continuing need for new tools to address an ever-changing array of fungal, weed and insect pests, NPs continue to be a source of models and templates for the development of new pest control agents. Interestingly, an examination of the literature suggests that NP models exist for many of the pest control agents that were discovered by other means, suggesting that, had circumstances been different, these NPs could have served as inspiration for the discovery of a great many more of today's pest control agents. Here, an attempt is made to answer questions regarding the existence of an NP model for existing classes of pesticides and what is needed for the discovery of new NPs and NP models for pest control agents. (C) 2014 Society of Chemical Industry