Harnessing bacterial toxins to treat pain.
Harnessing bacterial toxins to treat pain.
复制标题
利用细菌毒素来治疗疼痛。
DOI:
10.1038/s41593-021-00981-8
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发表时间:
2022
影响因子:
25
通讯作者:
Perez-Sanchez J
中科院分区:
文献类型:
--
作者:
Perez-Sanchez J
Yang et al. demonstrate that sensory neurons are enriched for the anthrax toxin receptor-2. Edema toxin, which acts via this receptor, induces analgesia in mice and can also be engineered to deliver large cargoes such as botulinum toxin in order to selectively silence sensory neurons.