Gender-related differences in lateralization of hippocampal activation and cognitive strategy
Gender-related differences in lateralization of hippocampal activation and cognitive strategy
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DOI：
10.1097/01.wnr.0000203623.02082.e3
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发表时间：
2006-03-20
期刊：
影响因子：
1.7
通讯作者：
Schulze-Bonhage, A
中科院分区：
文献类型：
--
作者：
Frings, L;Wagner, K;Schulze-Bonhage, A
在语言、情绪和工作记忆领域，已经报道了大脑激活模式的性别差异及其与认知功能相关的偏侧化。差异被假设是由于不同的认知策略。本研究的目的是测试在记忆处理过程中大脑半球激活的偏侧化是否在性别之间存在差异。我们从健康的女性和男性研究参与者中获取功能性磁共振成像数据，进行空间记忆任务，并定量评估每个参与者海马激活的偏侧化。女性的海马激活明显偏向左侧，男性则偏向右侧。相应地，女性认为她们的策略比男性更口头化。NeuroReport 17：417-421（c）2006 Lippincott威廉姆斯和威尔金斯。
Gender-related differences in brain activation patterns and their lateralization associated with cognitive functions have been reported in the field of language, emotion, and working memory. Differences have been hypothesized to be due to different cognitive strategies. The aim of the present study was to test whether lateralization of brain activation in the hippocampi during memory processing differs between the sexes. We acquired functional magnetic resonance imaging data from healthy female and male study participants performing a spatial memory task and quantitatively assessed the lateralization of hippocampal activation in each participant. Hippocampal activation was significantly more left lateralized in women, and more right lateralized in men. Correspondingly, women rated their strategy as being more verbal than men did. NeuroReport 17:417-421 (c) 2006 Lippincott Williams & Wilkins.