TreeQTL: hierarchical error control for eQTL findings

TreeQTL: hierarchical error control for eQTL findings
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TreeQTL:eQTL 结果的分层错误控制

DOI:
10.1101/021170
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发表时间:
2015
期刊:
bioRxiv
影响因子:
--
通讯作者:
C. Sabatti
C. Sabatti
中科院分区:
--
文献类型:
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作者:
Christine B. Peterson;Marina Bogomolov;Y. Benjamini;C. Sabatti

文献摘要

被引文献

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Summary Commonly used multiplicity adjustments fail to control the error rate for reported findings in many expression quantitative trait loci (eQTL) studies. TreeQTL implements a stage-wise multiple testing procedure which allows control of appropriate error rates defined relative to a hierarchical grouping of the eQTL hypotheses. Availability and Implementation The R package TreeQTL is available for download at http://bioinformatics.org/treeqtl. Contact sabatti@stanford.edu