The neural control of cyclic motor activity in the fetal rat (Rattus norvegicus).
The neural control of cyclic motor activity in the fetal rat (Rattus norvegicus).
复制标题
胎鼠（褐家鼠）循环运动活动的神经控制。
DOI：
10.1016/0031-9384(90)90049-a
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发表时间：
1990
影响因子：
2.9
通讯作者：
Smotherman,WP
中科院分区：
文献类型：
--
作者：
Robertson,SS;Smotherman,WP
在妊娠第20天直接观察大鼠胎仔的自发行为（在盐水浴中，胎仔-胎盘-子宫连接完整）30分钟。分析了胸中段脊髓横断或假手术胎儿的后肢和非后肢运动的周期性组织。在脊髓横断（0.74周期/min）和假手术（0.72周期/min）的胎儿中，后肢活动的振荡频率相同。然而，在脊髓横断的胎儿中，非后腿活动的振荡要慢得多（0.30 vs. 0.77 cycle/min）。运动活动周期模式的其他特征不受影响。结果表明：（1）脊髓尾侧在没有下行输入的情况下也能产生周期性输出;（2）不存在单一的计时中枢;
The spontaneous behavior of rat fetuses (in a saline bath with fetal-placental-uterine connections intact) was observed directly for 30 minutes on Day 20 of gestation. Rearleg and nonrearleg movements from fetuses with a mid-thoracic spinal cord transection or sham operation were analyzed for cyclic organization. Oscillations in rearleg activity occurred at the same frequency in fetuses with spinal cord transections (0.74 cycle/min) and sham-operated fetuses (0.72 cycle/min). However, oscillations in nonrearleg activity were much slower in the fetuses with spinal cord transections (0.30 vs. 0.77 cycle/min). Other characteristics of the cyclic patterns in motor activity were unaffected. The findings demonstrate 1) the caudal half of the spinal cord can generate cyclic output in the absence of descending input from the brain, 2) there is no single timing center, and 3) rostral sources are slower.