Is benign MS really benign? What a meaningful classification beyond the EDSS must take into consideration

Is benign MS really benign? What a meaningful classification beyond the EDSS must take into consideration
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DOI:
10.1016/j.msard.2020.102485
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发表时间:
2020-11-01
影响因子:
4
通讯作者:
Rommer, Paulus S.
Rommer, Paulus S.
中科院分区:
医学3区
文献类型:
--
作者:
Ellenberger, David;Flachenecker, Peter;Rommer, Paulus S.

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背景资料:多发性硬化症(MS)是一种神经炎症和神经退行性疾病,具有不可预测的过程,具有广泛的临床谱并随时间推移而进展。如果患有MS(PwMS)的人即使在长期患病后仍显示出总体轻度至中度残疾,则使用术语良性MS(BMS)。然而,目前还没有普遍接受的BMS定义。大多数定义基于与疾病持续时间相关的EDSS,即EDSS
Background: Multiple sclerosis (MS) is a neuroinflammatory and neurodegenerative disease with an unpredictable course that has a broad clinical spectrum and progresses over time. If a person with MS (PwMS) shows overall mild to moderate disability even after a long duration of disease, the term benign MS (BMS) is used. However, there is currently no generally accepted definition of BMS. Most definitions are based on EDSS in connection with disease duration, i.e. EDSS