ALKALINE-PHOSPHATASE POSITIVE PRECURSORS OF ADIPOCYTES IN THE HUMAN-BONE MARROW
ALKALINE-PHOSPHATASE POSITIVE PRECURSORS OF ADIPOCYTES IN THE HUMAN-BONE MARROW
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DOI：
10.1111/j.1365-2141.1988.tb04225.x
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发表时间：
1988-04-01
影响因子：
6.5
通讯作者：
BONUCCI, E
中科院分区：
文献类型：
--
作者：
BIANCO, P;COSTANTINI, M;BONUCCI, E
经化疗的白血病患者骨髓中发育中的脂肪细胞被赋予膜结合碱性磷酸酶。由于碱性磷酸酶是“网状”细胞的细胞化学标志物，这一观察结果提供了细胞化学证据，表明当骨髓细胞突然减少时，网状细胞可能转化为脂肪细胞。
Developing fat cells in the bone marrow of leukaemic patients treated with chemotherapy were found to be endowed with membrane-bound alkaline phosphatase. Since alkaline phosphatase is a cytochemical marker of ''reticular'' cells, this observation provides cytochemical evidence that reticular cells may convert to adipocytes when marrow cellularity abruptly decreases.