RANDOMIZE: A Web Server for Data Randomization

RANDOMIZE: A Web Server for Data Randomization
复制标题

RANDOMIZE:用于数据随机化的 Web 服务器

DOI:
--
复制
发表时间:
2020
期刊:
bioRxiv
影响因子:
--
通讯作者:
M. Uddin
M. Uddin
中科院分区:
--
文献类型:
--
作者:
A. Wani;Don Armstrong;J. Dahrendorff;M. Uddin

文献摘要

参考文献

相似文献

DNA甲基化微阵列数据可能会受到批次效应的影响,这是由于在平板接种过程中对样品的不当处理。RANDOMIZE是一个基于Web的应用程序,旨在执行相关元数据的随机化,以将样本均匀分布在通常导致DNA甲基化微阵列中批次效应的因素中,例如行,芯片和平板。随机化有助于减少偏倚的可能性和组间差异的影响。可用性该工具可在https://coph-usf.shinyapps.io/RANDOMIZE/上免费在线获得,并可使用任何Web浏览器访问。该工具还提供了示例数据和教程。联系ahwani@usf.edu
Summary DNA methylation microarray data may suffer from batch effects due to improper handling of the samples during the plating process. RANDOMIZE is a web-based application designed to perform randomization of relevant metadata to evenly distribute samples across the factors typically responsible for batch effects in DNA methylation microarrays, such as row, chips and plates. Randomization helps to reduce the likelihood of bias and impact of difference among groups. Availability The tool is freely available online at https://coph-usf.shinyapps.io/RANDOMIZE/ and can be accessed using any web browser. Sample data and tutorial is also available with the tool. Contact ahwani@usf.edu
DOI: 10.1093/biostatistics/kxj037
发表时间: 2007-01-01
期刊: BIOSTATISTICS
影响因子: 2.1
作者:
Johnson, W. Evan;Li, Cheng;Rabinovic, Ariel
通讯作者: Rabinovic, Ariel