Prognosis in colon cancer: a pathologic reassessment.
Prognosis in colon cancer: a pathologic reassessment.
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结肠癌的预后：病理学重新评估。
DOI：
10.1001/archsurg.1975.01360140052011
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发表时间：
1975
影响因子：
--
通讯作者：
L. Hampson
中科院分区：
文献类型：
--
作者：
D. Murray;A. Hreno;J. Dutton;L. Hampson
本文对148例结肠癌作了进一步的病理学研究。生存率与肿瘤的分期和分级以及受累淋巴结的数量相关。此外，病例还评估了病变周围局部慢性炎症反应的程度和引流淋巴结中窦组织细胞增多症的程度。分级、分期、淋巴结受累程度和生存率可能相关。当出现局部炎症反应和观察到窦组织细胞增生时，五年生存率有显著差异。这两种因素的存在进一步提高了生存率。充分评估这些因素，无论是单独或组合，应提高我们的能力，以评估结肠癌的预后。
One hundred forty-eight cases of colon carcinoma were subjected to further pathologic study. Survival was correlated with stage and grade of the tumor and with the number of involved lymph nodes. In addition, cases were assessed as to the extent of local chronic inflammatory reaction about the lesion and the degree of sinus histiocytosis in draining lymph nodes. A correlation was possible between grading, staging, extent of lymph node involvement, and survival. A substantial difference in five-year survival was shown when local inflammatory reaction was present and when sinus histiocytosis was observed. The presence of both of these factors further improved survival. An adequate evaluation of these factors, both individually and in combination, should improve our ability to assess prognosis in colon cancer.