Semantic and BCI-performance in completely paralyzed patients: Possibility of language attrition in completely locked in syndrome
Semantic and BCI-performance in completely paralyzed patients: Possibility of language attrition in completely locked in syndrome
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DOI：
10.1016/j.bandl.2019.05.004
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发表时间：
2019-07-01
影响因子：
2.5
通讯作者：
Chaudhary, Ujwal
中科院分区：
文献类型：
--
作者：
Ardali, Majid Khalili;Rana, Aygul;Chaudhary, Ujwal
完全闭锁综合征（CLIS）患者不能进行任何自主肌肉运动，也没有任何交流手段。最近，基于功能性近红外光谱（fNIRS）的脑机接口（BCI）已成功地用于与这些患者进行交流。开发的fNIRS-BCI系统依赖于这些患者在语言的各个方面的语言理解的完整性。语言和运动皮层交织在一起，长期缺乏肌肉活动，可导致CLIS患者因完全不动而导致语言磨损。在这项研究中，我们已经调查了句子的语义内容呈现给CLIS患者的BCI系统的性能在是/否范式的影响。不同语义类别的BCI分类中的通信成功率的比较表明，向CLIS患者呈现的句子的语义内容可以影响BCI性能。受影响的概念大多与执行词有关。这些发现可能有助于开发更可靠的通信设备，为患者在CLIS。此外，这些结果可能有助于阐明完全瘫痪患者自完全不动开始以来随着时间的推移而发生的认知变化。
Patients with completely locked-in syndrome (CLIS) are incapable of any voluntary muscle movement and do not have any means of communication. Recently functional near infrared spectroscopy (fNIRS) based brain computer interface (BCI) has been successfully used to enable communication with these patients. The developed fNIRS-BCI system relies on the intactness of language comprehension in these patients in all dimensions of language. Interwoven language and motor cortex in brain, and lack of muscular activity in long run, can cause language attrition due to complete immobility in CLIS patients. In this study we have investigated effects of semantic content of sentences presented to a CLIS patient on the performance of the BCI system during a YES/NO paradigm. Comparison of communication success rate in BCI classification between different semantic categories indicate that semantic content of sentences presented to a CLIS patient can affect the BCI performance. Affected concepts are mostly associated with executive words. These findings can be beneficial towards development of more reliable communication device for patients in CLIS. In addition, these results may assist in elucidating the cognitive changes in completely paralyzed patients with the passage of time since the onset of total immovability.