Cognitive inefficiency in depressive undergraduates: Stroop processing and ERPs
Cognitive inefficiency in depressive undergraduates: Stroop processing and ERPs
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DOI：
10.1016/j.biopsycho.2010.12.004
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发表时间：
2011-03-01
影响因子：
2.6
通讯作者：
Simons, Robert F.
中科院分区：
文献类型：
--
作者：
Krompinger, Jason W.;Simons, Robert F.
来自神经影像学研究的证据表明，抑郁症与执行任务时前额叶脑区的低效招募有关。在本研究中，我们调查的时间过程和ERP签名的低效率执行功能使用口头Stroop颜色命名任务。20名BDI-II抑郁评分为中度至重度的大学生和20名低评分对照完成了这项任务。两组之间的绩效指标没有差异。外显反应和P300潜伏期表明，所有的参与者都表现出突出的Stroop效应，这样，不一致的反应相比，一致的延迟。任务条件对额叶N450的影响表明，抑郁症参与者区分一致和不一致的试验早于对照组，和N450的一致性效应的大小与抑郁症参与者之间的自我报告特质反刍。在这种效应之后，抑郁的参与者表现出更大的P300，这表明抑郁的参与者对认知控制资源的过度承诺。这些数据提供了进一步的证据，皮质效率低下的假设，并延长文献表明可能不适当的时间在抑郁症大学生的执行任务的神经激活。(C)2010 Elsevier BV保留所有权利。
Evidence from neuroimaging studies indicates that depressive symptomatology is associated with inefficient recruitment of prefrontal brain regions while performing tasks that tax executive function. In the current study, we investigated the time-course and ERP signature of inefficient executive functioning using a verbal Stroop color-naming task. Twenty (20) undergraduates with moderate to severe BDI-II depression scores and 20 low-scoring controls completed the task. Performance measures did not differ between the two groups. Overt reaction and P300 latencies indicated that all participants showed prominent Stroop effects, such that incongruent responses were delayed compared to congruent. Effects of task condition on the frontal N450 indicated that depressive participants differentiated congruent and incongruent trials earlier than did controls, and that the size of the congruency effect on the N450 was related to self-reported trait rumination among depressive participants. Following this effect, depressive participants showed larger P300s, suggesting an over-commitment of cognitive control resources in the depressive participants. These data lend further evidence to the cortical inefficiency hypothesis and extend the literature by indicating possible improper timing of neural activations during an executive task in depressive undergraduates. (C) 2010 Elsevier B.V. All rights reserved.