The low FODMAP diet improves gastrointestinal symptoms in patients with irritable bowel syndrome: a prospective study
The low FODMAP diet improves gastrointestinal symptoms in patients with irritable bowel syndrome: a prospective study
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DOI：
10.1111/ijcp.12128
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发表时间：
2013-09-01
影响因子：
2.6
通讯作者：
Gearry, R. B.
中科院分区：
文献类型：
--
作者：
de Roest, R. H.;Dobbs, B. R.;Gearry, R. B.
背景和目的：目前肠易激综合征（IBS）的治疗是次优的。可发酵的低聚、二聚、单聚和多元醇（FODMAPs）可能引发IBS患者的胃肠道症状。我们的目的是确定低FODMAP饮食是否能改善IBS患者的症状。研究方法：肠易激综合征患者，谁进行了果糖和乳糖吸收不良的氢/甲烷呼吸测试，并已收到有关低FODMAP饮食的饮食建议，被纳入。使用症状问卷前瞻性评估了低FODMAP饮食的影响。此外，还评估了关于依从性和对症状改善、饮食建议和饮食的满意度的问题。结果：90例患者平均随访15.7个月。腹痛、腹胀、胀气、腹泻等症状明显改善（p
Background and aim: Current treatment for irritable bowel syndrome (IBS) is suboptimal. Fermentable oligo-, di-, mono-saccharides and polyols (FODMAPs) may trigger gastrointestinal symptoms in IBS patients. Our aim was to determine whether a low FODMAP diet improves symptoms in IBS patients. Methods: Irritable bowel syndrome patients, who had performed hydrogen/methane breath testing for fructose and lactose malabsorption and had received dietary advice regarding the low FODMAP diet, were included. The effect of low FODMAP diet was prospectively evaluated using a symptom questionnaire. Furthermore, questions about adherence and satisfaction with symptom improvement, dietary advice and diet were assessed. Results: Ninety patients with a mean follow up of 15.7months were studied. Most symptoms including abdominal pain, bloating, flatulence and diarrhoea significantly improved (p