Event-related brain potentials reflect increased concentration ability after mindfulness-based cognitive therapy for depression: A randomized clinical trial
Event-related brain potentials reflect increased concentration ability after mindfulness-based cognitive therapy for depression: A randomized clinical trial
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DOI：
10.1016/j.psychres.2012.05.031
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发表时间：
2012-10-30
影响因子：
11.3
通讯作者：
Hautzinger, Martin
中科院分区：
文献类型：
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作者：
Bostanov, Vladimir;Keune, Philipp M.;Hautzinger, Martin
基于正念的认知疗法（MBCT）有效地预防了重度抑郁症的复发/复发。将注意力部署和保持在特定焦点上的能力被认为是“正念”、“元认知”意识的先决条件，因此对治疗成功至关重要。因此，持续的专注是正念认知疗法中最广泛教授的技能。本研究的目的是测试这种能力是否增加后MBCT，假设。以事件相关脑电位（ERP）的关联性负变（CNV）的晚期成分作为集中能力的测量指标，该成分反映了注意力资源的分配。在研究的主要阶段，91名复发性抑郁症患者在缓解期被随机分配到8周的治疗，无论是MBCT或等待（等待延迟MBCT）。CNV对听觉测试刺激的反应是在治疗前和治疗后的“正念任务”中测量的，在该任务中，患者被指示专注于他们的呼吸，如MBCT中所教导的。晚期CNV（LCNV）仅在MBCT后增加（而不是在WAIT后）。这一结果反映了患者在轻度焦虑状态下将注意力转移到当前体验并远离潜在的致抑郁思维或沉思的能力提高-这是抑郁复发/复发的已知风险因素。(C)2012爱思唯尔爱尔兰有限公司保留所有权利。
Mindfulness-based cognitive therapy (MBCT) effectively prevents relapse/recurrence in major depression. The ability to deploy and maintain attention on a particular focus is considered as a prerequisite for 'mindful', 'metacognitive' awareness, and hence crucial for therapy success. Accordingly, sustained concentration is the skill most extensively taught in MBCT. The goal of the present study was to test whether this ability increases after MBCT, as assumed. The late component of the contingent negative variation (CNV), an event-related brain potential (ERP), known to reflect the allocation of attentional resources, was used as the measure of concentration ability. In the main phase of the study, 91 recurrently depressed patients in remission were randomly assigned to eight-week treatment by either MBCT or waiting (WAIT for delayed MBCT). The CNV response to an auditory test stimulus was measured pre- and post-treatment in a 'mindfulness task', in which patients were instructed to focus on their breath, as taught in MBCT. The late CNV (LCNV) was increased only after MBCT (and not after WAIT). This result reflects patients' improved ability to shift their attention toward current moment experience and away from potentially depressogenic thinking or rumination during mild dysphoric states-a known risk factor for depressive relapse/recurrence. (C) 2012 Elsevier Ireland Ltd. All rights reserved.