Revealing the genetic architecture of FHB resistance in hexaploid wheat (Triticum aestivum L.) by QTL meta-analysis
Revealing the genetic architecture of FHB resistance in hexaploid wheat (Triticum aestivum L.) by QTL meta-analysis
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DOI：
10.1007/s11032-008-9250-y
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发表时间：
2009-04-01
影响因子：
3.1
通讯作者：
Miedaner, Thomas
中科院分区：
文献类型：
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作者：
Loeffler, Martin;Schoen, Chris-Carolin;Miedaner, Thomas
小麦赤霉病（FHB）导致产量和品质下降，并导致真菌毒素的积累。本研究的目的是确定基因组区域参与控制赤霉病抗性应用QTL荟萃分析的方法，结合QTL的30个作图群体提出独立的元QTL（MQTL）。创建了一个共有图谱，在其上预测了初始QTL。在12条染色体上共检测到19个QTL，包含2-13个初始QTL，初始QTL的置信区间差异很大。其中一些QTL与先前鉴定的基因组区域（如3BS、6 B染色体）相吻合，但也有一些是本研究新发现的。对同一抗病亲本群体的分离分析表明，中国春小麦供体“苏麦3号”的一致性较高，而中国供体“王水白”和瑞士供体“Arina”的一致性较差。根据我们的研究结果，育种家可以在未来（1）选择不包含相同的抗性位点或QTL区间的杂交亲本，（2）开发新的QTL，（3）选择这些QTL中的一些标记用于标记辅助选择。
Fusarium head blight (FHB) in wheat results in reduced yield and quality and in accumulation of mycotoxins. The objective of this study was to identify genomic regions in wheat involved in the control of FHB resistance applying a QTL meta-analysis approach by combining QTL of 30 mapping populations to propose independent meta-QTL (MQTL). A consensus map was created on which initial QTL were projected. Nineteen MQTL comprising 2-13 initial QTL with widely varying confidence intervals were found on 12 chromosomes. Some of them coincided with genomic regions previously identified (e.g. chromosomes 3BS, 6B), however, some MQTL were newly detected by this study. Separate analysis of populations with the same resistant parent showed a rather high consistency for the Chinese spring wheat donor 'Sumai 3', but little consistency for the Chinese donor 'Wangshuibai' and the Swiss donor 'Arina'. According to our results breeders can in future (1) choose parents for crossing not comprising the same resistance loci or QTL intervals, (2) exploit new MQTL, and (3) select markers of some of these MQTL to be used in marker-assisted selection.