RISK-FACTORS AND HIV SEROPOSITIVITY AMONG INJECTING DRUG-USERS IN BANGKOK
RISK-FACTORS AND HIV SEROPOSITIVITY AMONG INJECTING DRUG-USERS IN BANGKOK
复制标题
DOI：
10.1097/00002030-199112000-00014
复制
发表时间：
1991-12-01
期刊：
影响因子：
3.8
通讯作者：
FRIEDMAN, SR
中科院分区：
文献类型：
--
作者：
CHOOPANYA, K;VANICHSENI, S;FRIEDMAN, SR
1987年和1988年，曼谷经历了艾滋病毒在注射吸毒者中极其迅速的传播。这项研究考察了艾滋病毒感染的风险因素，以及注射吸毒者刻意降低风险的努力。1989年11月招募了注射吸毒者的两个样本，一组是吸毒治疗组(n=342)，另一组是新加入治疗系统的组(n=259)。受试者接受了关于艾滋病危险行为的采访，并采集了血液样本进行艾滋病毒检测。在正在治疗的样本和新治疗的样本中，血清阳性率分别为39%和27%。治疗中样本的血清阳性率与6个月前和12个月前观察到的比率相似。与HIV感染独立相关的三个因素是：样本不足，曾在监狱服刑，以及在过去6个月内与两个或两个以上个人共用注射设备。92%的人报告了故意降低风险的情况，59%的人报告说他们已经停止共享注射设备。看来，大规模的风险降低大大减缓了艾滋病毒在曼谷注射吸毒者中的传播速度。
Bangkok experienced an extremely rapid spread of HIV infection among drug injectors in 1987 and 1988. This study examines risk factors for HIV infection and deliberate risk-reduction efforts by drug injectors. Two subsamples of injecting drug users were recruited in November 1989, a group in drug-use treatment (n = 342) and a group new to the treatment system (n = 259). Subjects were interviewed about AIDS risk behavior, and a blood sample was collected for HIV testing. Seroprevalence was 39 and 27% in the in-treatment sample and the new-to-treatment sample, respectively. The in-treatment sample seroprevalence rate is similar to rates observed 6 and 12 months earlier. Three factors were independently associated with HIV infection: subsample, having been in prison, and sharing injection equipment with two or more individuals in the previous 6 months. Deliberate risk reduction was reported by 92% of individuals, with 59% reporting that they had stopped sharing injection equipment. It appears that large-scale risk reduction has greatly slowed HIV transmission among drug injectors in Bangkok.